Cat. No.: 160 111AbOR
Amount: 100 µg
Price:
$465.00
|
|
|
| Cat. No. 160 111AbOR |
100 µg purified IgG, lyophilized, fluorescence-labeled with abberior STAR ORANGE.
abberior STAR® dyes have been especially developed for for Stimulated Emission Depletion (STED) microscopy which allows higher resolution imaging compared to confocal laser scanning microscopy. For many of the fluorescence labeled antibodies conjugated to abberior STAR® dyes established fluorescence detection systems can be used. This product or portions thereof is manufactured under license from abberior GmbH. Reconstitute immediately upon receipt! Avoid bright light when working with the antibody to minimize photo bleeching of the fluorescent dye. |
| Applications |
IP: N/A ICC: 1 : 300 (see remarks) gallery IHC: not tested yet IHC-P: not tested yet |
| Label | abberior STAR ORANGE |
| Clone | SY-72G2 |
| Subtype | IgG1 (κ light chain) |
| Immunogen | Recombinant protein corresponding to the c-terminal half of human Homer1b (UniProt Id: Q86YM7-1) |
| Reactivity |
Reacts with: mouse (Q9Z2Y3), rat (Q9Z214), human (Q86YM7-1). Other species not tested yet. |
| Specificity | Specific for Homer1b and 1c; no cross-reactivity to Homer1a |
| Remarks |
ICC: This antibody conjugate is especially suitable for high resolution STED microscopy. |
| Data sheet | 160_111abor.pdf |
|
|
Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, homer was suggested to organize distinct signalling domains.
Three isoforms, Homer1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.