Tailor-made Antibodies
and Tools for Life Science

Homer1b/c antibody - 160 023

Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors
Rabbit polyclonal purified antibody
Cat. No.: 160 023
Amount: 50 µg
Price: $465.00
Cat. No. 160 023 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 200 up to 1 : 500 gallery  
IHC-P: not tested yet
EM: yes
Immunogen Recombinant protein corresponding to the c-terminal half of human Homer 1b (UniProt Id: Q86YM7-1)
Reactivity Reacts with: human (Q86YM7-1), rat (Q9Z214-2, Q9Z214-1), mouse.
Other species not tested yet.
Specificity Specific for homer 1b and 1c; no cross-reactivity to homer 1a.
Matching control protein/peptide 160-02P
Data sheet 160_023.pdf

References for Homer1b/c - 160 023

A single 24 h maternal separation at PND 9 promotes behavioral resilience of female C57BL/6J mice and the possible role of hippocampal Homer1a.
Hao Y, Niu Y, Shi F, Zhang L, Peng C, Yan Z, Chen X, Xu H
Heliyon (2024) 105: e27037. 160 023 WB; tested species: mouse
Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation.
Tao-Cheng JH, Thein S, Yang Y, Reese TS, Gallant PE
Neuroscience (2014) 266: 80-90. 160 023 WB, EM; tested species: rat
Dysregulated postsynaptic density and endocytic zone in the amygdala of human heroin and cocaine abusers.
Okvist A, Fagergren P, Whittard J, Garcia-Osta A, Drakenberg K, Horvath MC, Schmidt CJ, Keller E, Bannon MJ, Hurd YL
Biological psychiatry (2011) 693: 245-52. 160 023 WB; tested species: human
Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways.
Roselli F, Hutzler P, Wegerich Y, Livrea P, Almeida OF
PloS one (2009) 46: e6011. 160 023 WB; tested species: rat
Cat. No.: 160 023
Amount: 50 µg
Price: $465.00