Home|||||||Technical Support|

Homer 1 - 160 011BT

A post synaptic density (PSD) protein involved in the targeting of glutamate receptors
Monoclonal mouse purified IgG
Cat. No.: 160 011BT
Amount: 100 µg
Price: $465.00
Cat. No. 160 011BT 100 µg purified IgG, lyophilized, biotin-labeled. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining)
IP: yes
ICC: 1 : 100 up to 1 : 500 gallery  
IHC: not tested yet
IHC-P/FFPE: not tested yet
Label biotin
Clone 2G8
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 196 from human Homer1 (UniProt Id: Q86YM7)
Epitop Epitop: AA 1 to 168 from human Homer1 (UniProt Id: Q86YM7)
Reactivity Reacts with: human (Q86YM7), rat (Q9Z214), mouse (Q9Z2Y3).
Other species not tested yet.
Specificity Specific for Homer 1. According to Soloviev et al. (2000), aa 1 - 180 are present in isoforms a, b, c and d.
Matching control protein/peptide 160-0P
Data sheet 160_011bt.pdf
Cat. No.: 160 011BT
Quantity: 100 µg
Price: $465.00
Background

Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, homer was suggested to organize distinct signalling domains.
Three isoforms, Homer 1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.