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VGAT antibody cytoplasmic domain - 131 006

VGAT or VIAAT is the GABA and glycine transporter in the membrane of synaptic vesicles
Polyclonal chicken purified antibody
Cat. No.: 131 006
Amount: 50 µg
Price: $370.00
Cat. No. 131 006 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: not recommended
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 2 to 115 from rat VGAT (UniProt Id: O35458)
Reactivity Reacts with: rat (O35458), mouse (O35633), human (Q9H598).
Other species not tested yet.
Specificity Specific for VGAT.
Matching control protein/peptide 131-0GP
Data sheet 131_006.pdf

References for VGAT - 131 006

Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons.
Pelkey KA, Calvigioni D, Fang C, Vargish G, Ekins T, Auville K, Wester JC, Lai M, Mackenzie-Gray Scott C, Yuan X, Hunt S, et al.
eLife (2020) 9: . 131 006 IHC; tested species: mouse
The Presynaptic Protein Mover Is Differentially Expressed Across Brain Areas and Synapse Types.
Wallrafen R, Dresbach T
Frontiers in neuroanatomy (2018) 12: 58. 131 006 IHC; tested species: mouse
Enhanced GABAergic Immunoreactivity in Hippocampal Neurons and Astroglia of Multiple Sclerosis Patients.
Kiljan S, Prins M, Baselmans BM, Bol JGJM, Schenk GJ, van Dam AM
Journal of neuropathology and experimental neurology (2019) 786: 480-491. 131 006 IHC-P; tested species: human
Cat. No.: 131 006
Quantity: 50 µg
Price: $370.00
Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons.
Pelkey KA, Calvigioni D, Fang C, Vargish G, Ekins T, Auville K, Wester JC, Lai M, Mackenzie-Gray Scott C, Yuan X, Hunt S, et al.
eLife (2020) 9: . 131 006 IHC; tested species: mouse
The Presynaptic Protein Mover Is Differentially Expressed Across Brain Areas and Synapse Types.
Wallrafen R, Dresbach T
Frontiers in neuroanatomy (2018) 12: 58. 131 006 IHC; tested species: mouse
Enhanced GABAergic Immunoreactivity in Hippocampal Neurons and Astroglia of Multiple Sclerosis Patients.
Kiljan S, Prins M, Baselmans BM, Bol JGJM, Schenk GJ, van Dam AM
Journal of neuropathology and experimental neurology (2019) 786: 480-491. 131 006 IHC-P; tested species: human
Background
The vesicular GABA transporter VGAT is responsible for uptake and storage of GABA and glycine by synaptic vesicles in the central nervous system. For this reason it is frequently referred to as the vesicular inhibitory aminoacid transporter VIAAT. It is different from the plasma membrane transporters in that it is driven by a proton electrochemical gradient across the vesicle membrane. So far, only one isoform is known. VGAT is currently the best marker for inhibitory nerve terminals.