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Syntaxin 12/13 antibody - 110 133

Syntaxin12/13 is a syntaxin family member functioning in the recycling of plasma membrane receptors
Polyclonal rabbit purified antibody
Cat. No.: 110 133
Amount: 50 µg
Price: $450.00
Cat. No. 110 133 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 100 up to 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 100 up to 1 : 500 gallery  
IHC: not tested yet
IHC-P/FFPE: 1 : 200 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 250 from rat Syntaxin12/13 (UniProt Id: G3V7P1)
Reactivity Reacts with: human (Q86Y82), rat (G3V7P1), mouse (Q9ER00), hamster, chicken.
Other species not tested yet.
Specificity Specific for syntaxin 12/13.
Matching control protein/peptide 110-13P
Data sheet 110_133.pdf

References for Syntaxin 12/13 - 110 133

A trap mutant reveals the physiological client spectrum of TRC40.
Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach B
Journal of cell science (2019) 13213: . 110 133 WB; tested species: human
Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes.
Yap CC, Digilio L, McMahon LP, Garcia ADR, Winckler B
The Journal of cell biology (2018) : . 110 133 WB; tested species: rat
GRASP1 Regulates Synaptic Plasticity and Learning through Endosomal Recycling of AMPA Receptors.
Chiu SL, Diering GH, Ye B, Takamiya K, Chen CM, Jiang Y, Niranjan T, Schwartz CE, Wang T, Huganir RL
Neuron (2017) 936: 1405-1419.e8. 110 133 WB; tested species: rat
Transmembrane and ubiquitin-like domain-containing protein 1 (Tmub1/HOPS) facilitates surface expression of GluR2-containing AMPA receptors.
Yang H, Takagi H, Konishi Y, Ageta H, Ikegami K, Yao I, Sato S, Hatanaka K, Inokuchi K, Seog DH, Setou M, et al.
PloS one (2008) 37: e2809. 110 133 WB; tested species: mouse,rat
Multispectral imaging reveals the tissue distribution of tetraspanins in human lymphoid organs.
de Winde CM, Zuidscherwoude M, Vasaturo A, van der Schaaf A, Figdor CG, van Spriel AB
Histochemistry and cell biology (2015) 1442: 133-46. 110 133 ICC
Cat. No.: 110 133
Quantity: 50 µg
Price: $450.00
A trap mutant reveals the physiological client spectrum of TRC40.
Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach B
Journal of cell science (2019) 13213: . 110 133 WB; tested species: human
Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes.
Yap CC, Digilio L, McMahon LP, Garcia ADR, Winckler B
The Journal of cell biology (2018) : . 110 133 WB; tested species: rat
GRASP1 Regulates Synaptic Plasticity and Learning through Endosomal Recycling of AMPA Receptors.
Chiu SL, Diering GH, Ye B, Takamiya K, Chen CM, Jiang Y, Niranjan T, Schwartz CE, Wang T, Huganir RL
Neuron (2017) 936: 1405-1419.e8. 110 133 WB; tested species: rat
Transmembrane and ubiquitin-like domain-containing protein 1 (Tmub1/HOPS) facilitates surface expression of GluR2-containing AMPA receptors.
Yang H, Takagi H, Konishi Y, Ageta H, Ikegami K, Yao I, Sato S, Hatanaka K, Inokuchi K, Seog DH, Setou M, et al.
PloS one (2008) 37: e2809. 110 133 WB; tested species: mouse,rat
Multispectral imaging reveals the tissue distribution of tetraspanins in human lymphoid organs.
de Winde CM, Zuidscherwoude M, Vasaturo A, van der Schaaf A, Figdor CG, van Spriel AB
Histochemistry and cell biology (2015) 1442: 133-46. 110 133 ICC
Background
Syntaxin 12/13 are orthologues of the same gene whose product is a member of the SNARE family of proteins. It is related to syntaxins 1-4 but is localized predominantly to early endosomes of a wide variety of cells. Syntaxin 12/13 appears to be involved in the recycling of membrane receptors such as the transferrin receptors where it mediates the fusion of endosomal membranes.