Tailor-made Antibodies
and Tools for Life Science

Synaptotagmin1 antibody luminal domain - 105 104

Synaptotagmin1 is a Ca2+-sensor on synaptic vesicles that triggers neurotransmitter release
Guinea pig polyclonal antiserum
Cat. No.: 105 104
Amount: 100 µl
Price: $370.00
Cat. No. 105 104 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 2000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 5000 (see remarks) gallery  
IHC: 1 : 500 gallery  
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 1 to 8 from mouse Synaptotagmin1 (UniProt Id: P46096)
Reactivity Reacts with: rat (P21707).
Other species not tested yet.

For unknown reasons antibodies raised against the luminal N-terminus of Synaptotagmin 1 show a strong preference for the rat protein.
Matching control protein/peptide 105-10P
Remarks

ICC: This antibody is intended to be used for direct labeling of recycling synapses in primary neuronal cultures.

Data sheet 105_104.pdf

References for Synaptotagmin1 - 105 104

Neural Cell Adhesion Molecule 2 (NCAM2)-Induced c-Src-Dependent Propagation of Submembrane Ca2+ Spikes Along Dendrites Inhibits Synapse Maturation.
Sheng L, Leshchyns'ka I, Sytnyk V
Cerebral cortex (New York, N.Y. : 1991) (2018) : . 105 104 ICC; tested species: mouse
Neuronal profilin isoforms are addressed by different signalling pathways.
Murk K, Wittenmayer N, Michaelsen-Preusse K, Dresbach T, Schoenenberger CA, Korte M, Jockusch BM, Rothkegel M
PloS one (2012) 73: e34167. 105 104 ICC; tested species: rat
Cat. No.: 105 104
Amount: 100 µl
Price: $370.00