Cat. No.: 285 002
Amount: 200 µl
Price:
$355.00
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| Cat. No. 285 002 |
200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet |
| Immunogen | Recombinant protein corresponding to AA 1 to 91 from mouse USP9x (UniProt Id: P70398) |
| Reactivity |
Reacts with: rat, mouse (P70398). Other species not tested yet. |
| Data sheet | 285_002.pdf |
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Ubiquitinylation of proteins regulates their stability and turnover and is involved in many cellular processes like endocytosis, cell-cycle regulation, transcriptional activation, etc.
Ubiquitin can be removed by deubiquitylating enzymes (DUBs) comprising ubiquitin specific proteases (USPs), or ubiquitin C-terminal hydrolases (UCHs).
Fat facets in mouse (FAM, also known as Usp9X) is a developmentally regulated UBP modulating ubiquitinylation of proteins like β-catenin, α-synuclein and others.