Cat. No.: 181-0P
Amount: 100 µg
Price:
$105.00
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| Cat. No. 181-0P |
100 µg protein, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in TBS. Then aliquot and store at -20°C to -80°C until use. Control proteins should be stored at +4°C when still lyophilized. Do not freeze! |
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| Recommended dilution | Optimal concentrations should be determined by the end-user. |
| Remarks |
This control protein consists of the recombinant protein (aa 1 - 250 of human TRIM 9) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen. |
| Data sheet | 181-0p.pdf |
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TRIM 9, also referred to as Spring, is a member of the tripartite motif protein family. These proteins are composed of three zinc-binding domains, a RING, a B-box type 1, a B-box type 2 and a coiled-coil region. Proteins belonging to this large family are involved in cellular processes ranging from cell-growth and development to the regulation of fusion events necessary for exocytosis.
TRIM 9 is expressed selectively in the adult and embryonic nervous system and has been implicated in the regulation of synaptic vesicle exocytosis via SNAP 25 interaction. Several splice variant with molecular weights from 60 - 80 kDa have been described.