Tailor-made Antibodies
and Tools for Life Science
quick order | cart
?
|
login
Home|||||Technical Support
Home > Products > 110 123

Syntaxin2 antibody - 110 123 K.D.

Syntaxin2 is an ubiquitous plasma membrane protein involved in fusion of vesicles with the plasma membrane
Rabbit polyclonal purified antibody
Cat. No.: 110 123
Amount: 50 µg
Price: $455.00
Cat. No. 110 123 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 100 gallery  
IHC: yes
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 265 from rat Syntaxin2 (UniProt Id: P50279)
Reactivity Reacts with: human (P32856), rat (P50279), mouse (Q00262), hamster.
Other species not tested yet.
Specificity K.D. validated PubMed: 36316316
Matching control protein/peptide 110-2P
Data sheet 110_123.pdf

References for Syntaxin2 - 110 123

The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release rely on the integrity of the C-terminal half of the SNARE domain of syntaxin-1A.
Salazar Lázaro A, Trimbuch T, Vardar G, Rosenmund C
eLife (2024) 12: . 110 123 WB, ICC; tested species: mouse
Plasma membrane flipping of Syntaxin-2 regulates its inhibitory action on insulin granule exocytosis.
Kang F, Xie L, Qin T, Miao Y, Kang Y, Takahashi T, Liang T, Xie H, Gaisano HY
Nature communications (2022) 131: 6512. 110 123 WB, IP; KD verified; tested species: human,mouse
SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.
Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, et al.
JCI insight (2020) 53: . 110 123 WB; tested species: human,mouse
Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 123 WB; tested species: mouse
Invasion by activated macrophages requires delivery of nascent MT1-MMP through late endosomes/lysosomes to the cell surface.
Röhl J, West ZE, Rudolph M, Zaharia A, Van Lonkhuyzen D, Hickey DK, Semmler ABT, Murray RZ
Traffic (Copenhagen, Denmark) (2019) : . 110 123 WB; tested species: mouse
Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini.
Falkowski MA, Thomas DD, Groblewski GE
The Journal of biological chemistry (2010) 28546: 35558-66. 110 123 WB
Plasma membrane flipping of Syntaxin-2 regulates its inhibitory action on insulin granule exocytosis.
Kang F, Xie L, Qin T, Miao Y, Kang Y, Takahashi T, Liang T, Xie H, Gaisano HY
Nature communications (2022) 131: 6512. 110 123 WB, IP; KD verified; tested species: human,mouse
The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release rely on the integrity of the C-terminal half of the SNARE domain of syntaxin-1A.
Salazar Lázaro A, Trimbuch T, Vardar G, Rosenmund C
eLife (2024) 12: . 110 123 WB, ICC; tested species: mouse
Spatial proteomics in neurons at single-protein resolution.
Unterauer EM, Shetab Boushehri S, Jevdokimenko K, Masullo LA, Ganji M, Sograte-Idrissi S, Kowalewski R, Strauss S, Reinhardt SCM, Perovic A, Marr C, et al.
Cell (2024) 1877: 1785-1800.e16. 110 123 DNA-PAINT; tested species: rat
Cat. No.: 110 123
Amount: 50 µg
Price: $455.00
The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release rely on the integrity of the C-terminal half of the SNARE domain of syntaxin-1A.
Salazar Lázaro A, Trimbuch T, Vardar G, Rosenmund C
eLife (2024) 12: . 110 123 WB, ICC; tested species: mouse
Plasma membrane flipping of Syntaxin-2 regulates its inhibitory action on insulin granule exocytosis.
Kang F, Xie L, Qin T, Miao Y, Kang Y, Takahashi T, Liang T, Xie H, Gaisano HY
Nature communications (2022) 131: 6512. 110 123 WB, IP; KD verified; tested species: human,mouse
SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.
Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, et al.
JCI insight (2020) 53: . 110 123 WB; tested species: human,mouse
Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 123 WB; tested species: mouse
Invasion by activated macrophages requires delivery of nascent MT1-MMP through late endosomes/lysosomes to the cell surface.
Röhl J, West ZE, Rudolph M, Zaharia A, Van Lonkhuyzen D, Hickey DK, Semmler ABT, Murray RZ
Traffic (Copenhagen, Denmark) (2019) : . 110 123 WB; tested species: mouse
Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini.
Falkowski MA, Thomas DD, Groblewski GE
The Journal of biological chemistry (2010) 28546: 35558-66. 110 123 WB
Plasma membrane flipping of Syntaxin-2 regulates its inhibitory action on insulin granule exocytosis.
Kang F, Xie L, Qin T, Miao Y, Kang Y, Takahashi T, Liang T, Xie H, Gaisano HY
Nature communications (2022) 131: 6512. 110 123 WB, IP; KD verified; tested species: human,mouse
The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release rely on the integrity of the C-terminal half of the SNARE domain of syntaxin-1A.
Salazar Lázaro A, Trimbuch T, Vardar G, Rosenmund C
eLife (2024) 12: . 110 123 WB, ICC; tested species: mouse
Spatial proteomics in neurons at single-protein resolution.
Unterauer EM, Shetab Boushehri S, Jevdokimenko K, Masullo LA, Ganji M, Sograte-Idrissi S, Kowalewski R, Strauss S, Reinhardt SCM, Perovic A, Marr C, et al.
Cell (2024) 1877: 1785-1800.e16. 110 123 DNA-PAINT; tested species: rat
WB
ICC
Background

Syntaxin 2, also referred to as Epimorphin, a member of the SNARE family of proteins, is related to syntaxin 1. Like syntaxin 4 it is predominantly localized to the plasma membrane of a wide variety of cells.
Similar to syntaxins 1, 3 and 4, it appears to be involved in the fusion of transport vesicles with the plasma membrane.
Other products for this target