Cat. No. 110 113 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
Applications | |
Immunogen | Synthetic peptide corresponding to AA 1 to 15 from mouse Syntaxin11 (UniProt Id: Q9D3G5) |
Reactivity |
Reacts with: rat (A0A0G2K516), mouse (Q9D3G5), human (O75558). Other species not tested yet. |
Specificity | K.O. validated |
Matching control protein/peptide | 110-11P |
Data sheet | 110_113.pdf |
Syntaxin 11, a member of the SNARE family of proteins, localizes to late endosomes and the trans-Golgi network and has been shown to interact with VAMP proteins and SNAP 23. Unlike other syntaxins it does not possess a carboxy-terminal transmembrane anchor.
In the immune systems several cell types like phagocytic immune cells, resting natural killer (NK) cells and CD8-T-cells express syntaxin 11. High levels of protein can also be found in lung and placenta but not in brain where it is almost undetectable.