Cat. No.: 157 002
Amount: 200 µl
Price:
$355.00
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| Cat. No. 157 002 |
200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 1274 to 1293 from rat SynGAP (UniProt Id: Q9QUH6) |
| Reactivity |
Reacts with: rat (Q9QUH6). Other species not tested yet. |
| Specificity | Recognizes both isofoms SynGAP a and b. |
| Matching control protein/peptide | 157-0P |
| Data sheet | 157_002.pdf |
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SynGAP is an approximately 135 kDa protein which is condensed at the post-synaptic density. A potential interaction partner for this protein is the abundant PDZ domain protein PSD 95.
Three isoforms (a, b and c) of synGAP have been described. The protein is a substrate for calmodulin dependent kinase 2 (CAMK2). Phosphorylation of synGAP reduces its activity, leading to an increased activation of Ras.