Cat. No.: 243 203
Amount: 50 µg
Price:
$375.00
|
|
|
| Cat. No. 243 203 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to AA 167 to 181 from mouse SynCAM2 (UniProt Id: Q8BLQ9) |
| Reactivity |
Reacts with: rat (Q1WIM2), mouse (Q8BLQ9), human (Q8N3J6). Other species not tested yet. |
| Specificity | K.O. validated PubMed: 29217450 |
| Matching control protein/peptide | 243-2P |
| Data sheet | 243_203.pdf |
|
|
Development of synapses involves transsynaptic interactions of dedicated synaptic adhesion molecules like neuroligins, neurexins and synCAMs (Synaptic cell adhesion molecules). Four SynCAM isoforms have been described so far. All share a common domain structure and contain three extracellular Ig domains, a single transmembrane region, and a short COOH-terminal cytoplasmic tail.
SynCAM 2 has been shown to be associated to myelinated axons and synCAM 3 can serve as a receptor for herpes viruses.