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Home > Products > 268 103

SUMO1 antibody - 268 103

SUMO1 belongs to the ubiquitin like proteins
Rabbit polyclonal purified antibody
Cat. No.: 268 103
Amount: 50 µg
Price: $375.00
Cat. No. 268 103 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: not tested yet
ICC: 1 : 1000 gallery  
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 2 to 20 from mouse SUMO1 (UniProt Id: P63166)
Reactivity Reacts with: human (P63165), rat (Q5I0H3), mouse (P63166).
Other species not tested yet.
Matching control protein/peptide 268-1P
Remarks

WB: Cat. no. 268 003 is superior for westernblotting
Data sheet 268_103.pdf
Cat. No.: 268 103
Amount: 50 µg
Price: $375.00
WB
ICC
Background
The Small ubiquitin-related modifiers SUMOs are ubiquitin-like proteins (UBLs) that can be conjugated to other proteins in a manner analogous to ubiquitin. Four SUMO paralogs, SUMO 1-4 have been described in mammals. SUMO 1 is also referred to as GMP 1, Setrin 1, SMT3C and SMT3H3.
Modification of proteins with SUMO 1 or other SUMOs requires a unique activating enzyme complex as well as a conjugation enzyme. This process plays an important role in a wide variety of processes such as transcriptional regulation, maintenance of genome integrity and subcellular localization.
Sumoylated proteins include PML, Sp100, IκBα, RanGAP1and RANBP2. The unmodified 70 kDa form of RanGAP1 is exclusively cytoplasmic, whereas the 90 kDa sumoylated form is associated with the cytoplasmic fibers of nuclear pore complexes (NPCs).
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