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SNAP23 antibody - 111 213

SNAP23 is a palmitoylated plasma membrane protein; ubiquitously expressed isoform of SNAP 25
Rabbit polyclonal purified antibody
Cat. No.: 111 213
Amount: 50 µg
Price: $375.00
Cat. No. 111 213 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes (see remarks)
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 86 to 210 from mouse SNAP23 (UniProt Id: O09044)
Reactivity Reacts with: rat (O70377), mouse (O09044).
Other species not tested yet.
Remarks

IP: This antibody is most efficient and recommended for immunoprecipitation.

Data sheet 111_213.pdf

References for SNAP23 - 111 213

EHD2 regulates plasma membrane integrity and downstream insulin receptor signalling events.
Neuhaus M, Fryklund C, Taylor H, Borreguero-Muñoz A, Kopietz F, Ardalani H, Rogova O, Stirrat L, Bremner SK, Spégel P, Bryant NJ, et al.
Molecular biology of the cell (2023) : mbcE23030078. 111 213 WB, ICC; tested species: mouse
SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons.
Asraf H, Bogdanovic M, Gottesman N, Sekler I, Aizenman E, Hershfinkel M
iScience (2022) 252: 103751. 111 213 IP, DNA-PAINT; tested species: mouse
EHD2 regulates plasma membrane integrity and downstream insulin receptor signalling events.
Neuhaus M, Fryklund C, Taylor H, Borreguero-Muñoz A, Kopietz F, Ardalani H, Rogova O, Stirrat L, Bremner SK, Spégel P, Bryant NJ, et al.
Molecular biology of the cell (2023) : mbcE23030078. 111 213 WB, ICC; tested species: mouse
SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons.
Asraf H, Bogdanovic M, Gottesman N, Sekler I, Aizenman E, Hershfinkel M
iScience (2022) 252: 103751. 111 213 IP, DNA-PAINT; tested species: mouse
Cat. No.: 111 213
Amount: 50 µg
Price: $375.00
EHD2 regulates plasma membrane integrity and downstream insulin receptor signalling events.
Neuhaus M, Fryklund C, Taylor H, Borreguero-Muñoz A, Kopietz F, Ardalani H, Rogova O, Stirrat L, Bremner SK, Spégel P, Bryant NJ, et al.
Molecular biology of the cell (2023) : mbcE23030078. 111 213 WB, ICC; tested species: mouse
SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons.
Asraf H, Bogdanovic M, Gottesman N, Sekler I, Aizenman E, Hershfinkel M
iScience (2022) 252: 103751. 111 213 IP, DNA-PAINT; tested species: mouse
EHD2 regulates plasma membrane integrity and downstream insulin receptor signalling events.
Neuhaus M, Fryklund C, Taylor H, Borreguero-Muñoz A, Kopietz F, Ardalani H, Rogova O, Stirrat L, Bremner SK, Spégel P, Bryant NJ, et al.
Molecular biology of the cell (2023) : mbcE23030078. 111 213 WB, ICC; tested species: mouse
SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons.
Asraf H, Bogdanovic M, Gottesman N, Sekler I, Aizenman E, Hershfinkel M
iScience (2022) 252: 103751. 111 213 IP, DNA-PAINT; tested species: mouse
Background

SNAP23 (synaptosome-associated protein of 23 kDa) is an ubiquitously expressed isoform and functional homologue of SNAP25. It is resistant to cleavage by BoNT/A and E. The protein is part of the exocytotic fusion complex (v-SNARE) where it assembles with syntaxin1 and synaptobrevin.
SNAP23 is able to function in regulated exocytosis. Both isoforms may have their own specific binding partners and discrete, albeit mechanistically similar, functional roles within the cell.