Cat. No.: 162 202
Amount: 200 µl
Price:
$355.00
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| Cat. No. 162 202 |
200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to residues near the carboxy terminus of rat Shank2 (UniProt Id: Q9QX74) |
| Reactivity |
Reacts with: rat (Q9QX74), mouse (Q80Z38). Other species not tested yet. |
| Specificity | K.O. validated PubMed: 29572432 |
| Remarks |
IHC: This antibody requires mild fixation with 1% PFA at low pH (pH 6.0). |
| Data sheet | 162_202.pdf |
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Shank1, 2 and 3 are major proteins of the postsynaptic density (PSD). They are composed of several protein-protein interaction domains like PDZ-, homer- and ABP1-binding domains which allow them to crosslink ionotopic and metabotropic glutamate receptor complexes with each other and to the actin-cytoskeleton.