Cat. No.: 124 315
Amount: 50 µg
Price:
$460.00
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| Cat. No. 124 315 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: yes ICC: not recommended IHC: not tested yet IHC-P: not tested yet |
| Immunogen | Recombinant protein corresponding to AA 1 to 130 from rat SAP97 (UniProt Id: Q62696) |
| Reactivity |
Reacts with: rat (Q62696), mouse (Q811D0). Other species not tested yet. |
| Specificity | Shows band of expected size in westernblots. |
| Data sheet | 124_315.pdf |
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SAP 97 (synapse associated protein of 97 kDa, also called DLG 1) like PSD 95 and SAP 102, is a scaffolding protein of the postsynaptic density. It consists of three type-one PDZ domains and binds selectively to the C-terminus of the GluR1 subunit of AMPA receptors.
SAP 97 is probably involved in the clustering of AMPA receptors at the post-synaptic membrane.
It is also expressed in heart, where it has been shown to be involved in the targeting of voltage gated potassium channels to subpopulations of lipid rafts.