Cat. No.: 105 133
Amount: 50 µg
Price:
$375.00
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| Cat. No. 105 133 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 123 to 154 from human Synaptotagmin3 (UniProt Id: Q9BQG1) |
| Reactivity |
Reacts with: rat (P40748), mouse (O35681), human (Q9BQG1). Other species not tested yet. |
| Specificity | K.O. validated PubMed: 30545844 |
| Data sheet | 105_133.pdf |
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Up to now at least 17 synaptotagmins have been identified. Like other proteins of this family synaptotagmin3 is composed of a vesicular, a transmembrane and two C2 domains.
Synaptotagmin3 is expressed in brain, where it localizes to synaptic plasma membranes, and also in non-neuronal cells. In pancreatic islet β-cells it is involved in Ca2+ triggered insulin secretion, and in basophilic leukemia mast cells (RBL-cells) in transport events to the perinuclear endocytic recycling compartment.