Cat. No.: 103 204
Amount: 100 µl
Price:
$365.00
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| Cat. No. 103 204 |
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not recommended IHC-P: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 211 to 224 from rat Synaptogyrin2 (UniProt Id: O54980) |
| Reactivity |
Reacts with: human (O43760), rat (O54980), mouse (O55101). Other species not tested yet. |
| Matching control protein/peptide | 103-02P |
| Data sheet | 103_204.pdf |
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Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal (synaptogyrin 1 and 3) and one ubiquitous, synaptogyrin 2 or cellugyrin isoform.
Synaptogyrins are integral membrane proteins and localize to the membrane of small vesicles. Synaptogyrin 1 and 3 are expressed in the brain whereby the latter shows a more restricted expression pattern with high levels in the mossy fiber region of the hippocampus, substantia nigra pars reticulata, pallidum, and deep cerebellar nuclei.
Synaptogyrin 2/cellugyrin, a close relative, is expressed in all tissues, for instance, in distinct populations of GLUT 4 containing vesicles.