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Home > Products > 426 003

RNF126 antibody - 426 003

RNF126 is an E3 Ubiquitin Ligase
Rabbit polyclonal purified antibody
Cat. No.: 426 003
Amount: 50 µg
Price: $375.00
Cat. No. 426 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 AP staining gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.

Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen Recombinant protein corresponding to AA 1 to 100 from human RNF126 (UniProt Id: Q9BV68)
Reactivity Reacts with: human (Q9BV68), rat (Q499Q1), mouse (Q91YL2).
Other species not tested yet.
Data sheet 426_003.pdf
Cat. No.: 426 003
Amount: 50 µg
Price: $375.00
WB
WB
Background

RNF 126 is an E3 ubiquitin ligase that collaborates with the BAG6 sortase complex to ubiquitinate hydrophobic substrates in the cytoplasm that are targeted for proteasomal recycling.

It belongs to the family of RING E3 ligases and consists of an N-terminal zinc-finger  and a C- terminal RING domain.

RNF 126 has also been shown to be involved in promotion of cancer growth.