Cat. No.: 244 002
Amount: 200 µl
Price:
$355.00
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| Cat. No. 244 002 |
200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: yes (see remarks) ICC: not tested yet (see remarks) IHC: not tested yet IHC-P: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 1448 to 1464 from mouse GluN2A (UniProt Id: P35436) |
| Reactivity |
Reacts with: rat (Q00959, Q00960), mouse (P35436, Q01097). Other species not tested yet. |
| Specificity | Cross-reacts to GluN 2B due to sequence homology. |
| Matching control protein/peptide | 244-0P |
| Remarks |
IP: For most effective IP, use the denaturing IP-protocol. Consider that protein-protein interactions may be affected. |
| Data sheet | 244_002.pdf |
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GluNs (NMDA-receptors) represent a class of glutamate receptors that are of central importance in synaptic plasticity. Multiple NMDA receptor subtypes exist: GluN1 and GluN2 A-D. GluN1 is the most important as it is required for activity. NMDA-receptors allow Ca2+ influx and are thought to trigger Ca2+ dependent postsynaptic processes involved in long term potentiation and depression.