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Home > Products > 368 003

Kv7.3 antibody - 368 003

Kv7.3 is a potassium channel widely expressed throughout the brain
Rabbit polyclonal purified antibody
Cat. No.: 368 003
Amount: 50 µg
Price: $375.00
Cat. No. 368 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not recommended
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 858 to 873 from rat Kv7.3 (UniProt Id: O88944-1)
Reactivity Reacts with: rat (O88944), mouse (Q8K3F6).
Other species not tested yet.
Matching control protein/peptide 368-0P
Data sheet 368_003.pdf

References for Kv7.3 - 368 003

Molecular and functional profiling of cell diversity and identity in the lateral superior olive, an auditory brainstem center with ascending and descending projections.
Maraslioglu-Sperber A, Pizzi E, Fisch JO, Kattler K, Ritter T, Friauf E
Frontiers in cellular neuroscience (2024) 18: 1354520. 368 003 IHC; tested species: mouse
Cat. No.: 368 003
Amount: 50 µg
Price: $375.00
Molecular and functional profiling of cell diversity and identity in the lateral superior olive, an auditory brainstem center with ascending and descending projections.
Maraslioglu-Sperber A, Pizzi E, Fisch JO, Kattler K, Ritter T, Friauf E
Frontiers in cellular neuroscience (2024) 18: 1354520. 368 003 IHC; tested species: mouse
WB
Background
Five voltage gated potassium channels Kv7, encoded by the genes KCNQ 1-5, have been described in mammals so far. They are integral membrane proteins and show distinct distribution patterns. Kv7.2, Kv7.3 and Kv7.5 are widely expressed in different brain regions whereas Kv7.1 and Kv7.4 show more restricted expression profiles.
Kv7.3 forms the M channel with either Kv7.2 or Kv7.5. This ion channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability.
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