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HSP90 beta antibody - 380 103 K.D.

Heat shock proteins 90 (HSP90) are molecular chaperones
Rabbit polyclonal purified antibody
Cat. No.: 380 103
Amount: 50 µg
Price: $375.00
Cat. No. 380 103 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 639 to 709 from human HSP90 β (UniProt Id: P08238)
Reactivity Reacts with: human (P08238), rat (P82995), mouse (P11499).
Other species not tested yet.
Specificity K.D. validated
Matching control protein/peptide 380-1P
Data sheet 380_103.pdf
Cat. No.: 380 103
Amount: 50 µg
Price: $375.00
Background
Heat shock proteins 90 (HSP 90) are molecular chaperones. Two isoforms (α and β) have been described so far. They promote the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. They undergo a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation.
HSP 90s interact dynamically with various co-chaperones that modulate their substrate recognition, ATPase cycle and chaperone function.