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Home > Products > 173 004
- will be discontinued soon
Polyclonal antibodies are a finite resource. We have now started to sell the last lots of our well received Guinea pig polyclonal GFAP antibody 173 004. It will be replaced by our new Guinea pig monoclonal recombinant IgG GFAP antibody 173 308.

GFAP antibody - 173 004 K.O.

GFAP is an astrocyte-specific type-III intermediate filament protein
Guinea pig polyclonal antiserum
Cat. No.: 173 004
Amount: 100 µl
Price: $400.00
Cat. No. 173 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 1000 gallery  
IHC-P: 1 : 1000 gallery  
Immunogen full-length recombinant human GFAP (UniProt Id: P14136)
Reactivity Reacts with: human (P14136), rat (P47819), mouse (P03995), chicken, sheep.
Other species not tested yet.
Specificity Specific for GFAP, detects all isoforms. K.O. validated
Matching control protein/peptide 173-0P
Data sheet 173_004.pdf

References for GFAP - 173 004

Resident Astrocytes can Limit Injury to Developing Hippocampal Neurons upon THC Exposure.
Krassnitzer M, Boisvert B, Beiersdorf J, Harkany T, Keimpema E
Neurochemical research (2022) : . 173 004 WB, IHC; tested species: mouse
Sex Differences in Metabolic Recuperation After Weight Loss in High Fat Diet-Induced Obese Mice.
Guerra-Cantera S, Frago LM, Collado-Pérez R, Canelles S, Ros P, Freire-Regatillo A, Jiménez-Hernaiz M, Barrios V, Argente J, Chowen JA
Frontiers in endocrinology (2021) 12: 796661. 173 004 WB; tested species: mouse
Impact of Long-Term HFD Intake on the Peripheral and Central IGF System in Male and Female Mice.
Guerra-Cantera S, Frago LM, Jiménez-Hernaiz M, Ros P, Freire-Regatillo A, Barrios V, Argente J, Chowen JA
Metabolites (2020) 1011: . 173 004 WB; tested species: mouse
SUMO1-conjugation is altered during normal aging but not by increased amyloid burden.
Stankova T, Piepkorn L, Bayer TA, Jahn O, Tirard M
Aging cell (2018) : e12760. 173 004 WB; tested species: mouse
Tanycytes and a differential fatty acid metabolism in the hypothalamus.
Hofmann K, Lamberz C, Piotrowitz K, Offermann N, But D, Scheller A, Al-Amoudi A, Kuerschner L
Glia (2017) 652: 231-249. 173 004 IHC, WB; tested species: mouse
Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons.
Ripamonti S, Ambrozkiewicz MC, Guzzi F, Gravati M, Biella G, Bormuth I, Hammer M, Tuffy LP, Sigler A, Kawabe H, Nishimori K, et al.
eLife (2017) 6: . 173 004 WB; tested species: mouse
Dual Role of the P2X7 Receptor in Dendritic Outgrowth during Physiological and Pathological Brain Development.
Mut-Arbona P, Huang L, Baranyi M, Tod P, Iring A, Calzaferri F, de Los Ríos C, Sperlágh B
The Journal of neuroscience : the official journal of the Society for Neuroscience (2023) 437: 1125-1142. 173 004 ICC; tested species: mouse
Reproducible and scalable differentiation of highly pure cortical neurons from human induced pluripotent stem cells.
Dannert A, Klimmt J, Cardoso Gonçalves C, Crusius D, Paquet D
STAR protocols (2023) 42: 102266. 173 004 ICC; tested species: human
Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF.
Antoniou A, Auderset L, Kaurani L, Sebastian E, Zeng Y, Allahham M, Cases-Cunillera S, Schoch S, Gruendemann J, Fischer A, Schneider A, et al.
Cell reports (2023) 422: 112063. 173 004 ICC; tested species: mouse
Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function.
Pratt KJB, Shea JM, Remesal-Gomez L, Bieri G, Smith LK, Couthouis J, Chen CP, Roy IJ, Gontier G, Villeda SA
Cell reports (2022) 416: 111612. 173 004 ICC; tested species: mouse
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak G, Rybak-Wolf A, Lisowski P, Pentimalli TM, Jüttner R, Glažar P, Uppal K, Bottani E, Brunetti D, Secker C, Zink A, et al.
Nature communications (2021) 121: 1929. 173 004 ICC; tested species: human
Isolation and functional characterization of primary endothelial cells from mouse cerebral cortex.
Ouellette J, Lacoste B
STAR protocols (2021) 24: 101019. 173 004 ICC; tested species: mouse
Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia.
Bassil R, Shields K, Granger K, Zein I, Ng S, Chih B
Nature communications (2021) 121: 5220. 173 004 ICC; tested species: human
The histone demethylase PHF8 regulates astrocyte differentiation and function.
Iacobucci S, Padilla N, Gabrielli M, Navarro C, Lombardi M, Vicioso-Mantis M, Verderio C, de la Cruz X, Martínez-Balbás MA
Development (Cambridge, England) (2021) 14812: . 173 004 ICC; tested species: mouse
Matrix Metalloproteinase 14 Mediates APP Proteolysis and Lysosomal Alterations Induced by Oxidative Stress in Human Neuronal Cells.
Llorente P, Martins S, Sastre I, Aldudo J, Recuero M, Adjaye J, Bullido MJ
Oxidative medicine and cellular longevity (2020) 2020: 5917187. 173 004 ICC; tested species: human
IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network.
Martins S, Müller-Schiffmann A, Erichsen L, Bohndorf M, Wruck W, Sleegers K, Van Broeckhoven C, Korth C, Adjaye J
International journal of molecular sciences (2020) 2112: . 173 004 ICC; tested species: human
Human iPSC-Derived Down Syndrome Astrocytes Display Genome-Wide Perturbations in Gene Expression, an Altered Adhesion Profile, and Increased Cellular Dynamics.
Bally BP, Farmer WT, Jones EV, Jessa S, Kacerovsky JB, Mayran A, Peng H, Lefebvre JL, Drouin J, Hayer A, Ernst C, et al.
Human molecular genetics (2020) : . 173 004 ICC; tested species: human
Regulation of dendrite morphology and excitatory synapse formation by zDHHC15.
Shah BS, Shimell JJ, Bamji SX
Journal of cell science (2019) 13213: . 173 004 ICC; tested species: rat
An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.
Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, et al.
Cell reports (2019) 277: 2212-2228.e7. 173 004 ICC; tested species: mouse
Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex.
Stamou M, Grodzki AC, van Oostrum M, Wollscheid B, Lein PJ
Journal of neuroinflammation (2018) 151: 7. 173 004 ICC, FACS; tested species: rat
Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron cultures.
Valtcheva MV, Copits BA, Davidson S, Sheahan TD, Pullen MY, McCall JG, Dikranian K, Gereau RW
Nature protocols (2016) 1110: 1877-88. 173 004 ICC
Brief alcohol exposure alters transcription in astrocytes via the heat shock pathway.
Pignataro L, Varodayan FP, Tannenholz LE, Protiva P, Harrison NL
Brain and behavior (2013) 32: 114-33. 173 004 ICC
Lead exposure reduces survival, neuronal determination, and differentiation of P19 stem cells.
Mansel C, Fross S, Rose J, Dema E, Mann A, Hart H, Klawinski P, Vohra BPS
Neurotoxicology and teratology () 72: 58-70. 173 004 ICC; tested species: mouse
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, et al.
Immunity (2024) : . 173 004 IHC; tested species: mouse
Single-cell m6A profiling in the mouse brain uncovers cell type-specific RNA methylomes and age-dependent differential methylation.
Tegowski M, Prater AK, Holley CL, Meyer KD
Nature neuroscience (2024) : . 173 004 IHC; tested species: mouse
Dipeptidyl peptidase 4 deficiency improves survival after focal cerebral ischemia in mice and ameliorates microglia activation and specific inflammatory markers.
Höfling C, Donkersloot P, Ulrich L, Burghardt S, Opitz M, Geissler S, Schilling S, Cynis H, Michalski D, Roßner S
Neurobiology of disease (2024) 201: 106671. 173 004 IHC; tested species: mouse
Membrane properties and coupling of macroglia in the optic nerve.
Kompier N, Semtner M, Walter S, Kakabadze N, Steinhäuser C, Nolte C, Kettenmann H
Current research in neurobiology (2024) 7: 100137. 173 004 IHC; tested species: mouse
Microglia-astrocyte crosstalk in the amyloid plaque niche of an Alzheimer's disease mouse model, as revealed by spatial transcriptomics.
Mallach A, Zielonka M, van Lieshout V, An Y, Khoo JH, Vanheusden M, Chen WT, Moechars D, Arancibia-Carcamo IL, Fiers M, De Strooper B, et al.
Cell reports (2024) 436: 114216. 173 004 IHC; tested species: mouse
Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain.
Marty-Lombardi S, Lu S, Ambroziak W, Schrenk-Siemens K, Wang J, DePaoli-Roach AA, Hagenston AM, Wende H, Tappe-Theodor A, Simonetti M, Bading H, et al.
Nature metabolism (2024) : . 173 004 IHC; tested species: mouse
Comparative analyses of the Smith-Magenis syndrome protein RAI1 in mice and common marmoset monkeys.
Chang YT, Lee YJ, Haque M, Chang HC, Javed S, Lin YC, Cho Y, Abramovitz J, Chin G, Khamis A, Raja R, et al.
The Journal of comparative neurology (2024) 5321: e25589. 173 004 IHC; tested species: mouse,marmoset
iPSC-derived models of PACS1 syndrome reveal transcriptional and functional deficits in neuron activity.
Rylaarsdam L, Rakotomamonjy J, Pope E, Guemez-Gamboa A
Nature communications (2024) 151: 827. 173 004 IHC; tested species: human
The synaptic vesicle protein Mover/TPRG1L is associated with lipid droplets in astrocytes.
Krohn J, Domart F, Do TT, Dresbach T
Glia (2023) : . 173 004 IHC; tested species: mouse
Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson's disease.
Vidyadhara DJ, Somayaji M, Wade N, Yücel B, Zhao H, Shashaank N, Ribaudo J, Gupta J, Lam TT, Sames D, Greene LE, et al.
Cell reports (2023) 423: 112231. 173 004 IHC; tested species: mouse
Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus.
Iannitelli AF, Segal A, Pare JF, Mulvey B, Liles LC, Sloan SA, McCann KE, Dougherty JD, Smith Y, Weinshenker D
bioRxiv : the preprint server for biology (2023) : . 173 004 IHC; tested species: mouse
Neuronal activity dynamics in the dentate gyrus during early epileptogenesis.
Berglind F, Boulot A, Gonzalez-Ramos A, Melin E, Bono A, Sørensen AT, Ledri M
Epilepsy research (2023) 194: 107182. 173 004 IHC; tested species: mouse
Activation of β2-Adrenergic Receptors in Microglia Alleviates Neuropathic Hypersensitivity in Mice.
Damo E, Agarwal A, Simonetti M
Cells (2023) 122: . 173 004 IHC; tested species: mouse
Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance.
Wang N, Zhu B, Allnutt MA, Grijalva RM, Zhao H, Chandra SS
bioRxiv : the preprint server for biology (2023) : . 173 004 IHC; tested species: mouse
Impaired pre-synaptic plasticity and visual responses in auxilin-knockout mice.
Cheng X, Tang Y, Vidyadhara DJ, Li BZ, Zimmerman M, Pak A, Nareddula S, Edens PA, Chandra SS, Chubykin AA
iScience (2023) 2610: 107842. 173 004 IHC; tested species: mouse
Regionally Altered Immunosignals of Surfactant Protein-G, Vascular and Non-Vascular Elements of the Neurovascular Unit after Experimental Focal Cerebral Ischemia in Mice, Rats, and Sheep.
Michalski D, Reimann W, Spielvogel E, Mages B, Biedermann B, Barthel H, Nitzsche B, Schob S, Härtig W
International journal of molecular sciences (2022) 2311: . 173 004 IHC; tested species: mouse,sheep
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.
Shah D, Gsell W, Wahis J, Luckett ES, Jamoulle T, Vermaercke B, Preman P, Moechars D, Hendrickx V, Jaspers T, Craessaerts K, et al.
Cell reports (2022) 408: 111280. 173 004 IHC; tested species: human,mouse
Resident Astrocytes can Limit Injury to Developing Hippocampal Neurons upon THC Exposure.
Krassnitzer M, Boisvert B, Beiersdorf J, Harkany T, Keimpema E
Neurochemical research (2022) : . 173 004 WB, IHC; tested species: mouse
Midazolam prevents the adverse outcome of neonatal asphyxia.
Welzel B, Schmidt R, Johne M, Löscher W
Annals of neurology (2022) : . 173 004 IHC; tested species: rat
Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation.
Quadros ARAA, Arazola RD, Álvarez AR, Pires J, Meredith RM, Saarloos I, Verhage M, Toonen RF
iScience (2022) 254: 104069. 173 004 IHC; tested species: mouse
C21orf91 Regulates Oligodendroglial Precursor Cell Fate-A Switch in the Glial Lineage?
Reiche L, Göttle P, Lane L, Duek P, Park M, Azim K, Schütte J, Manousi A, Schira-Heinen J, Küry P
Frontiers in cellular neuroscience (2021) 15: 653075. 173 004 IHC; tested species: rat
Structural Degradation in Midcingulate Cortex Is Associated with Pathological Aggression in Mice.
Heukelum SV, Geers FE, Tulva K, van Dulm S, Beckmann CF, Buitelaar JK, Glennon JC, Vogt BA, Havenith MN, França ASC
Brain sciences (2021) 117: . 173 004 IHC; tested species: mouse
Light microscopic and heterogeneity analysis of astrocytes in the common marmoset brain.
Muñoz Y, Cuevas-Pacheco F, Quesseveur G, Murai KK
Journal of neuroscience research (2021) : . 173 004 IHC; tested species: marmoset
A central role for anterior cingulate cortex in the control of pathological aggression.
van Heukelum S, Tulva K, Geers FE, van Dulm S, Ruisch IH, Mill J, Viana JF, Beckmann CF, Buitelaar JK, Poelmans G, Glennon JC, et al.
Current biology : CB (2021) 3111: 2321-2333.e5. 173 004 IHC; tested species: mouse
Microglia sense neuronal activity via GABA in the early postnatal hippocampus.
Logiacco F, Xia P, Georgiev SV, Franconi C, Chang YJ, Ugursu B, Sporbert A, Kühn R, Kettenmann H, Semtner M
Cell reports (2021) 3713: 110128. 173 004 IHC; tested species: mouse
Astrocyte glutamate uptake coordinates experience-dependent, eye-specific refinement in developing visual cortex.
Sipe GO, Petravicz J, Rikhye RV, Garcia R, Mellios N, Sur M
Glia (2021) 697: 1723-1735. 173 004 IHC; tested species: mouse
Microglia and astrocytes show limited, acute alterations in morphology and protein expression following a single developmental alcohol exposure.
Lowery RL, Cealie MY, Lamantia CE, Mendes MS, Drew PD, Majewska AK
Journal of neuroscience research (2021) 998: 2008-2025. 173 004 IHC; tested species: mouse
Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking.
Schiweck J, Murk K, Ledderose J, Münster-Wandowski A, Ornaghi M, Vida I, Eickholt BJ
Nature communications (2021) 121: 1490. 173 004 IHC; tested species: mouse
Hypoxic-ischemic injury causes functional and structural neurovascular degeneration in the juvenile mouse retina.
Zaitoun IS, Shahi PK, Suscha A, Chan K, McLellan GJ, Pattnaik BR, Sorenson CM, Sheibani N
Scientific reports (2021) 111: 12670. 173 004 IHC; tested species: mouse
Increased Immunosignals of Collagen IV and Fibronectin Indicate Ischemic Consequences for the Neurovascular Matrix Adhesion Zone in Various Animal Models and Human Stroke Tissue.
Michalski D, Spielvogel E, Puchta J, Reimann W, Barthel H, Nitzsche B, Mages B, Jäger C, Martens H, Horn AKE, Schob S, et al.
Frontiers in physiology (2020) 11: 575598. 173 004 IHC; tested species: mouse,rat,sheep
Langat virus infection affects hippocampal neuron morphology and function in mice without disease signs.
Cornelius ADA, Hosseini S, Schreier S, Fritzsch D, Weichert L, Michaelsen-Preusse K, Fendt M, Kröger A
Journal of neuroinflammation (2020) 171: 278. 173 004 IHC; tested species: mouse
Molecular design of hypothalamus development.
Romanov RA, Tretiakov EO, Kastriti ME, Zupancic M, Häring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, et al.
Nature (2020) 5827811: 246-252. 173 004 IHC; tested species: mouse
Sustained Hypoxia Alters nTS Glutamatergic Signaling and Expression and Function of Excitatory Amino Acid Transporters.
Matott MP, Hasser EM, Kline DD
Neuroscience (2020) : . 173 004 IHC; tested species: mouse
Mechanically transformative electronics, sensors, and implantable devices.
Byun SH, Sim JY, Zhou Z, Lee J, Qazi R, Walicki MC, Parker KE, Haney MP, Choi SH, Shon A, Gereau GB, et al.
Science advances (2019) 511: eaay0418. 173 004 IHC; tested species: mouse
Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism.
Gong J, Szegő ÉM, Leonov A, Benito E, Becker S, Fischer A, Zweckstetter M, Outeiro T, Schneider A
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 173 004 IHC; tested species: mouse
Neuropathological findings suggestive for a stroke in an alpaca (Vicugna pacos).
Schöniger S, Schütze E, Michalski D, Puchta J, Kaiser M, Härtig W
Acta veterinaria Scandinavica (2019) 611: 1. 173 004 IHC
Reduced Smoothened level rescued Aβ-induced memory deficits and neuronal inflammation in animal models of Alzheimer's disease.
Ma W, Wu M, Zhou S, Tao Y, Xie Z, Zhong Y
Journal of genetics and genomics = Yi chuan xue bao (2018) : . 173 004 IHC; tested species: mouse
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.
Ogrodnik M, Zhu Y, Langhi LGP, Tchkonia T, Krüger P, Fielder E, Victorelli S, Ruswhandi RA, Giorgadze N, Pirtskhalava T, Podgorni O, et al.
Cell metabolism (2018) : . 173 004 IHC; tested species: mouse
Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia.
Hüttenrauch M, Ogorek I, Klafki H, Otto M, Stadelmann C, Weggen S, Wiltfang J, Wirths O
Acta neuropathologica communications (2018) 61: 108. 173 004 IHC; tested species: mouse
Hypoxia activates a neuropeptidergic pathway from the paraventricular nucleus of the hypothalamus to the nucleus tractus solitarii.
Ruyle BC, Klutho PJ, Baines CP, Heesch CM, Hasser EM
American journal of physiology. Regulatory, integrative and comparative physiology (2018) : . 173 004 IHC; tested species: rat
Radial glial elements in the cerebral cortex of the lesser hedgehog tenrec.
Mack AF, Künzle H, Lange M, Mages B, Reichenbach A, Härtig W
Brain structure & function (2018) : . 173 004 IHC
Tanycytes and a differential fatty acid metabolism in the hypothalamus.
Hofmann K, Lamberz C, Piotrowitz K, Offermann N, But D, Scheller A, Al-Amoudi A, Kuerschner L
Glia (2017) 652: 231-249. 173 004 IHC, WB; tested species: mouse
Delayed histochemical alterations within the neurovascular unit due to transient focal cerebral ischemia and experimental treatment with neurotrophic factors.
Michalski D, Pitsch R, Pillai DR, Mages B, Aleithe S, Grosche J, Martens H, Schlachetzki F, Härtig W
PloS one (2017) 124: e0174996. 173 004 IHC
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, et al.
Neuron (2017) 935: 1066-1081.e8. 173 004 IHC; tested species: human,mouse
Neurovascular Specifications in the Alzheimer-Like Brain of Mice Affected by Focal Cerebral Ischemia: Implications for Future Therapies.
Michalski D, Hofmann S, Pitsch R, Grosche J, Härtig W
Journal of Alzheimer's disease : JAD (2017) 592: 655-674. 173 004 IHC; tested species: mouse
Damaged Neocortical Perineuronal Nets Due to Experimental Focal Cerebral Ischemia in Mice, Rats and Sheep.
Härtig W, Mages B, Aleithe S, Nitzsche B, Altmann S, Barthel H, Krueger M, Michalski D
Frontiers in integrative neuroscience (2017) 11: 15. 173 004 IHC; tested species: mouse,rat,sheep
An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody.
Batiuk MY, de Vin F, Duqué SI, Li C, Saito T, Saido T, Fiers M, Belgard TG, Holt MG
The Journal of biological chemistry (2017) 29221: 8874-8891. 173 004 IHC; tested species: mouse
Excitatory amino acid transporters tonically restrain nTS synaptic and neuronal activity to modulate cardiorespiratory function.
Matott MP, Ruyle BC, Hasser EM, Kline DD
Journal of neurophysiology (2016) 1153: 1691-702. 173 004 IHC; tested species: rat
Dual roles of the adenosine A2a receptor in autoimmune neuroinflammation.
Ingwersen J, Wingerath B, Graf J, Lepka K, Hofrichter M, Schröter F, Wedekind F, Bauer A, Schrader J, Hartung HP, Prozorovski T, et al.
Journal of neuroinflammation (2016) 13: 48. 173 004 IHC
Immunohistochemical insights into Saffold virus infection of the brain of juvenile AG129 mice.
Tan SZ, Prabakaran M
Virology journal (2016) 131: 191. 173 004 IHC
Up-regulation of neurofilament light chains is associated with diminished immunoreactivities for MAP2 and tau after ischemic stroke in rodents and in a human case.
Härtig W, Krueger M, Hofmann S, Preißler H, Märkel M, Frydrychowicz C, Mueller WC, Bechmann I, Michalski D
Journal of chemical neuroanatomy (2016) 78: 140-148. 173 004 IHC
Relaxin increases sympathetic nerve activity and activates spinally projecting neurons in the paraventricular nucleus of nonpregnant, but not pregnant, rats.
Coldren KM, Brown R, Hasser EM, Heesch CM
American journal of physiology. Regulatory, integrative and comparative physiology (2015) 30912: R1553-68. 173 004 IHC; tested species: rat
Widespread expression of erythropoietin receptor in brain and its induction by injury.
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, et al.
Molecular medicine (Cambridge, Mass.) (2015) : . 173 004 IHC
Detection and Quantification of β-Amyloid, Pyroglutamyl Aβ, and Tau in Aged Canines.
Schmidt F, Boltze J, Jäger C, Hofmann S, Willems N, Seeger J, Härtig W, Stolzing A
Journal of neuropathology and experimental neurology (2015) 749: 912-23. 173 004 IHC
The capsaicin receptor TRPV1 as a novel modulator of neural precursor cell proliferation.
Stock K, Garthe A, de Almeida Sassi F, Glass R, Wolf SA, Kettenmann H
Stem cells (Dayton, Ohio) (2014) 3212: 3183-95. 173 004 IHC
Blood-brain barrier breakdown after embolic stroke in rats occurs without ultrastructural evidence for disrupting tight junctions.
Krueger M, Härtig W, Reichenbach A, Bechmann I, Michalski D
PloS one (2013) 82: e56419. 173 004 IHC
D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase.
Ehmsen JT, Ma TM, Sason H, Rosenberg D, Ogo T, Furuya S, Snyder SH, Wolosker H
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3330: 12464-9. 173 004 IHC
Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation.
Breunig JJ, Gate D, Levy R, Rodriguez J, Kim GB, Danielpour M, Svendsen CN, Town T
Neural development (2012) 7: 26. 173 004 IHC
Long-lasting neuronal loss following experimental focal cerebral ischemia is not affected by combined administration of tissue plasminogen activator and hyperbaric oxygen.
Hobohm C, Laignel F, Kacza J, Küppers-Tiedt L, Heindl M, Schneider D, Grosche J, Härtig W, Michalski D
Brain research (2011) 1417: 115-26. 173 004 IHC
Rapid Increases in proBDNF after Pilocarpine-Induced Status Epilepticus in Mice Are Associated with Reduced proBDNF Cleavage Machinery.
Thomas AX, Cruz Del Angel Y, Gonzalez MI, Carrel AJ, Carlsen J, Lam PM, Hempstead BL, Russek SJ, Brooks-Kayal AR
eNeuro () 31: . 173 004 IHC
Blood-Brain Barrier Leakage during Early Epileptogenesis Is Associated with Rapid Remodeling of the Neurovascular Unit.
Bankstahl M, Breuer H, Leiter I, Märkel M, Bascuñana P, Michalski D, Bengel FM, Löscher W, Meier M, Bankstahl JP, Härtig W, et al.
eNeuro () 53: . 173 004 IHC; tested species: rat
Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1.
Blumenreich S, Ben-Yashar DP, Shalit T, Kupervaser M, Milenkovic I, Joseph T, Futerman AH
Journal of neurochemistry (2024) 1681: 52-65. 173 004 IHC-P; tested species: mouse
Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease.
Marengo L, Armbrust F, Schoenherr C, Storck SE, Schmitt U, Zampar S, Wirths O, Altmeppen H, Glatzel M, Kaether C, Weggen S, et al.
Cellular and molecular life sciences : CMLS (2022) 793: 168. 173 004 IHC-P; tested species: mouse
SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?
Löhr M, Härtig W, Schulze A, Kroiß M, Sbiera S, Lapa C, Mages B, Strobel S, Hundt JE, Bohnert S, Kircher S, et al.
International journal of molecular sciences (2022) 237: . 173 004 IHC-P; tested species: human
Modulators of Neuroinflammation Have a Beneficial Effect in a Lafora Disease Mouse Model.
Mollá B, Heredia M, Sanz P
Molecular neurobiology (2021) 586: 2508-2522. 173 004 IHC-P; tested species: mouse
Innate immune response in neuronopathic forms of Gaucher disease confers resistance against viral-induced encephalitis.
Melamed S, Avraham R, Rothbard DE, Erez N, Israely T, Klausner Z, Futerman AH, Paran N, Vitner EB
Acta neuropathologica communications (2020) 81: 144. 173 004 IHC-P; tested species: mouse
Reactive Glia-Derived Neuroinflammation: a Novel Hallmark in Lafora Progressive Myoclonus Epilepsy That Progresses with Age.
Lahuerta M, Gonzalez D, Aguado C, Fathinajafabadi A, García-Giménez JL, Moreno-Estellés M, Romá-Mateo C, Knecht E, Pallardó FV, Sanz P
Molecular neurobiology (2019) : . 173 004 IHC-P; tested species: mouse
Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex.
Stamou M, Grodzki AC, van Oostrum M, Wollscheid B, Lein PJ
Journal of neuroinflammation (2018) 151: 7. 173 004 ICC, FACS; tested species: rat
Cat. No.: 173 004
Amount: 100 µl
Price: $400.00
Resident Astrocytes can Limit Injury to Developing Hippocampal Neurons upon THC Exposure.
Krassnitzer M, Boisvert B, Beiersdorf J, Harkany T, Keimpema E
Neurochemical research (2022) : . 173 004 WB, IHC; tested species: mouse
Sex Differences in Metabolic Recuperation After Weight Loss in High Fat Diet-Induced Obese Mice.
Guerra-Cantera S, Frago LM, Collado-Pérez R, Canelles S, Ros P, Freire-Regatillo A, Jiménez-Hernaiz M, Barrios V, Argente J, Chowen JA
Frontiers in endocrinology (2021) 12: 796661. 173 004 WB; tested species: mouse
Impact of Long-Term HFD Intake on the Peripheral and Central IGF System in Male and Female Mice.
Guerra-Cantera S, Frago LM, Jiménez-Hernaiz M, Ros P, Freire-Regatillo A, Barrios V, Argente J, Chowen JA
Metabolites (2020) 1011: . 173 004 WB; tested species: mouse
SUMO1-conjugation is altered during normal aging but not by increased amyloid burden.
Stankova T, Piepkorn L, Bayer TA, Jahn O, Tirard M
Aging cell (2018) : e12760. 173 004 WB; tested species: mouse
Tanycytes and a differential fatty acid metabolism in the hypothalamus.
Hofmann K, Lamberz C, Piotrowitz K, Offermann N, But D, Scheller A, Al-Amoudi A, Kuerschner L
Glia (2017) 652: 231-249. 173 004 IHC, WB; tested species: mouse
Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons.
Ripamonti S, Ambrozkiewicz MC, Guzzi F, Gravati M, Biella G, Bormuth I, Hammer M, Tuffy LP, Sigler A, Kawabe H, Nishimori K, et al.
eLife (2017) 6: . 173 004 WB; tested species: mouse
Dual Role of the P2X7 Receptor in Dendritic Outgrowth during Physiological and Pathological Brain Development.
Mut-Arbona P, Huang L, Baranyi M, Tod P, Iring A, Calzaferri F, de Los Ríos C, Sperlágh B
The Journal of neuroscience : the official journal of the Society for Neuroscience (2023) 437: 1125-1142. 173 004 ICC; tested species: mouse
Reproducible and scalable differentiation of highly pure cortical neurons from human induced pluripotent stem cells.
Dannert A, Klimmt J, Cardoso Gonçalves C, Crusius D, Paquet D
STAR protocols (2023) 42: 102266. 173 004 ICC; tested species: human
Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF.
Antoniou A, Auderset L, Kaurani L, Sebastian E, Zeng Y, Allahham M, Cases-Cunillera S, Schoch S, Gruendemann J, Fischer A, Schneider A, et al.
Cell reports (2023) 422: 112063. 173 004 ICC; tested species: mouse
Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function.
Pratt KJB, Shea JM, Remesal-Gomez L, Bieri G, Smith LK, Couthouis J, Chen CP, Roy IJ, Gontier G, Villeda SA
Cell reports (2022) 416: 111612. 173 004 ICC; tested species: mouse
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak G, Rybak-Wolf A, Lisowski P, Pentimalli TM, Jüttner R, Glažar P, Uppal K, Bottani E, Brunetti D, Secker C, Zink A, et al.
Nature communications (2021) 121: 1929. 173 004 ICC; tested species: human
Isolation and functional characterization of primary endothelial cells from mouse cerebral cortex.
Ouellette J, Lacoste B
STAR protocols (2021) 24: 101019. 173 004 ICC; tested species: mouse
Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia.
Bassil R, Shields K, Granger K, Zein I, Ng S, Chih B
Nature communications (2021) 121: 5220. 173 004 ICC; tested species: human
The histone demethylase PHF8 regulates astrocyte differentiation and function.
Iacobucci S, Padilla N, Gabrielli M, Navarro C, Lombardi M, Vicioso-Mantis M, Verderio C, de la Cruz X, Martínez-Balbás MA
Development (Cambridge, England) (2021) 14812: . 173 004 ICC; tested species: mouse
Matrix Metalloproteinase 14 Mediates APP Proteolysis and Lysosomal Alterations Induced by Oxidative Stress in Human Neuronal Cells.
Llorente P, Martins S, Sastre I, Aldudo J, Recuero M, Adjaye J, Bullido MJ
Oxidative medicine and cellular longevity (2020) 2020: 5917187. 173 004 ICC; tested species: human
IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network.
Martins S, Müller-Schiffmann A, Erichsen L, Bohndorf M, Wruck W, Sleegers K, Van Broeckhoven C, Korth C, Adjaye J
International journal of molecular sciences (2020) 2112: . 173 004 ICC; tested species: human
Human iPSC-Derived Down Syndrome Astrocytes Display Genome-Wide Perturbations in Gene Expression, an Altered Adhesion Profile, and Increased Cellular Dynamics.
Bally BP, Farmer WT, Jones EV, Jessa S, Kacerovsky JB, Mayran A, Peng H, Lefebvre JL, Drouin J, Hayer A, Ernst C, et al.
Human molecular genetics (2020) : . 173 004 ICC; tested species: human
Regulation of dendrite morphology and excitatory synapse formation by zDHHC15.
Shah BS, Shimell JJ, Bamji SX
Journal of cell science (2019) 13213: . 173 004 ICC; tested species: rat
An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.
Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, et al.
Cell reports (2019) 277: 2212-2228.e7. 173 004 ICC; tested species: mouse
Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex.
Stamou M, Grodzki AC, van Oostrum M, Wollscheid B, Lein PJ
Journal of neuroinflammation (2018) 151: 7. 173 004 ICC, FACS; tested species: rat
Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron cultures.
Valtcheva MV, Copits BA, Davidson S, Sheahan TD, Pullen MY, McCall JG, Dikranian K, Gereau RW
Nature protocols (2016) 1110: 1877-88. 173 004 ICC
Brief alcohol exposure alters transcription in astrocytes via the heat shock pathway.
Pignataro L, Varodayan FP, Tannenholz LE, Protiva P, Harrison NL
Brain and behavior (2013) 32: 114-33. 173 004 ICC
Lead exposure reduces survival, neuronal determination, and differentiation of P19 stem cells.
Mansel C, Fross S, Rose J, Dema E, Mann A, Hart H, Klawinski P, Vohra BPS
Neurotoxicology and teratology () 72: 58-70. 173 004 ICC; tested species: mouse
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, et al.
Immunity (2024) : . 173 004 IHC; tested species: mouse
Single-cell m6A profiling in the mouse brain uncovers cell type-specific RNA methylomes and age-dependent differential methylation.
Tegowski M, Prater AK, Holley CL, Meyer KD
Nature neuroscience (2024) : . 173 004 IHC; tested species: mouse
Dipeptidyl peptidase 4 deficiency improves survival after focal cerebral ischemia in mice and ameliorates microglia activation and specific inflammatory markers.
Höfling C, Donkersloot P, Ulrich L, Burghardt S, Opitz M, Geissler S, Schilling S, Cynis H, Michalski D, Roßner S
Neurobiology of disease (2024) 201: 106671. 173 004 IHC; tested species: mouse
Membrane properties and coupling of macroglia in the optic nerve.
Kompier N, Semtner M, Walter S, Kakabadze N, Steinhäuser C, Nolte C, Kettenmann H
Current research in neurobiology (2024) 7: 100137. 173 004 IHC; tested species: mouse
Microglia-astrocyte crosstalk in the amyloid plaque niche of an Alzheimer's disease mouse model, as revealed by spatial transcriptomics.
Mallach A, Zielonka M, van Lieshout V, An Y, Khoo JH, Vanheusden M, Chen WT, Moechars D, Arancibia-Carcamo IL, Fiers M, De Strooper B, et al.
Cell reports (2024) 436: 114216. 173 004 IHC; tested species: mouse
Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain.
Marty-Lombardi S, Lu S, Ambroziak W, Schrenk-Siemens K, Wang J, DePaoli-Roach AA, Hagenston AM, Wende H, Tappe-Theodor A, Simonetti M, Bading H, et al.
Nature metabolism (2024) : . 173 004 IHC; tested species: mouse
Comparative analyses of the Smith-Magenis syndrome protein RAI1 in mice and common marmoset monkeys.
Chang YT, Lee YJ, Haque M, Chang HC, Javed S, Lin YC, Cho Y, Abramovitz J, Chin G, Khamis A, Raja R, et al.
The Journal of comparative neurology (2024) 5321: e25589. 173 004 IHC; tested species: mouse,marmoset
iPSC-derived models of PACS1 syndrome reveal transcriptional and functional deficits in neuron activity.
Rylaarsdam L, Rakotomamonjy J, Pope E, Guemez-Gamboa A
Nature communications (2024) 151: 827. 173 004 IHC; tested species: human
The synaptic vesicle protein Mover/TPRG1L is associated with lipid droplets in astrocytes.
Krohn J, Domart F, Do TT, Dresbach T
Glia (2023) : . 173 004 IHC; tested species: mouse
Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson's disease.
Vidyadhara DJ, Somayaji M, Wade N, Yücel B, Zhao H, Shashaank N, Ribaudo J, Gupta J, Lam TT, Sames D, Greene LE, et al.
Cell reports (2023) 423: 112231. 173 004 IHC; tested species: mouse
Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus.
Iannitelli AF, Segal A, Pare JF, Mulvey B, Liles LC, Sloan SA, McCann KE, Dougherty JD, Smith Y, Weinshenker D
bioRxiv : the preprint server for biology (2023) : . 173 004 IHC; tested species: mouse
Neuronal activity dynamics in the dentate gyrus during early epileptogenesis.
Berglind F, Boulot A, Gonzalez-Ramos A, Melin E, Bono A, Sørensen AT, Ledri M
Epilepsy research (2023) 194: 107182. 173 004 IHC; tested species: mouse
Activation of β2-Adrenergic Receptors in Microglia Alleviates Neuropathic Hypersensitivity in Mice.
Damo E, Agarwal A, Simonetti M
Cells (2023) 122: . 173 004 IHC; tested species: mouse
Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance.
Wang N, Zhu B, Allnutt MA, Grijalva RM, Zhao H, Chandra SS
bioRxiv : the preprint server for biology (2023) : . 173 004 IHC; tested species: mouse
Impaired pre-synaptic plasticity and visual responses in auxilin-knockout mice.
Cheng X, Tang Y, Vidyadhara DJ, Li BZ, Zimmerman M, Pak A, Nareddula S, Edens PA, Chandra SS, Chubykin AA
iScience (2023) 2610: 107842. 173 004 IHC; tested species: mouse
Regionally Altered Immunosignals of Surfactant Protein-G, Vascular and Non-Vascular Elements of the Neurovascular Unit after Experimental Focal Cerebral Ischemia in Mice, Rats, and Sheep.
Michalski D, Reimann W, Spielvogel E, Mages B, Biedermann B, Barthel H, Nitzsche B, Schob S, Härtig W
International journal of molecular sciences (2022) 2311: . 173 004 IHC; tested species: mouse,sheep
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.
Shah D, Gsell W, Wahis J, Luckett ES, Jamoulle T, Vermaercke B, Preman P, Moechars D, Hendrickx V, Jaspers T, Craessaerts K, et al.
Cell reports (2022) 408: 111280. 173 004 IHC; tested species: human,mouse
Resident Astrocytes can Limit Injury to Developing Hippocampal Neurons upon THC Exposure.
Krassnitzer M, Boisvert B, Beiersdorf J, Harkany T, Keimpema E
Neurochemical research (2022) : . 173 004 WB, IHC; tested species: mouse
Midazolam prevents the adverse outcome of neonatal asphyxia.
Welzel B, Schmidt R, Johne M, Löscher W
Annals of neurology (2022) : . 173 004 IHC; tested species: rat
Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation.
Quadros ARAA, Arazola RD, Álvarez AR, Pires J, Meredith RM, Saarloos I, Verhage M, Toonen RF
iScience (2022) 254: 104069. 173 004 IHC; tested species: mouse
C21orf91 Regulates Oligodendroglial Precursor Cell Fate-A Switch in the Glial Lineage?
Reiche L, Göttle P, Lane L, Duek P, Park M, Azim K, Schütte J, Manousi A, Schira-Heinen J, Küry P
Frontiers in cellular neuroscience (2021) 15: 653075. 173 004 IHC; tested species: rat
Structural Degradation in Midcingulate Cortex Is Associated with Pathological Aggression in Mice.
Heukelum SV, Geers FE, Tulva K, van Dulm S, Beckmann CF, Buitelaar JK, Glennon JC, Vogt BA, Havenith MN, França ASC
Brain sciences (2021) 117: . 173 004 IHC; tested species: mouse
Light microscopic and heterogeneity analysis of astrocytes in the common marmoset brain.
Muñoz Y, Cuevas-Pacheco F, Quesseveur G, Murai KK
Journal of neuroscience research (2021) : . 173 004 IHC; tested species: marmoset
A central role for anterior cingulate cortex in the control of pathological aggression.
van Heukelum S, Tulva K, Geers FE, van Dulm S, Ruisch IH, Mill J, Viana JF, Beckmann CF, Buitelaar JK, Poelmans G, Glennon JC, et al.
Current biology : CB (2021) 3111: 2321-2333.e5. 173 004 IHC; tested species: mouse
Microglia sense neuronal activity via GABA in the early postnatal hippocampus.
Logiacco F, Xia P, Georgiev SV, Franconi C, Chang YJ, Ugursu B, Sporbert A, Kühn R, Kettenmann H, Semtner M
Cell reports (2021) 3713: 110128. 173 004 IHC; tested species: mouse
Astrocyte glutamate uptake coordinates experience-dependent, eye-specific refinement in developing visual cortex.
Sipe GO, Petravicz J, Rikhye RV, Garcia R, Mellios N, Sur M
Glia (2021) 697: 1723-1735. 173 004 IHC; tested species: mouse
Microglia and astrocytes show limited, acute alterations in morphology and protein expression following a single developmental alcohol exposure.
Lowery RL, Cealie MY, Lamantia CE, Mendes MS, Drew PD, Majewska AK
Journal of neuroscience research (2021) 998: 2008-2025. 173 004 IHC; tested species: mouse
Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking.
Schiweck J, Murk K, Ledderose J, Münster-Wandowski A, Ornaghi M, Vida I, Eickholt BJ
Nature communications (2021) 121: 1490. 173 004 IHC; tested species: mouse
Hypoxic-ischemic injury causes functional and structural neurovascular degeneration in the juvenile mouse retina.
Zaitoun IS, Shahi PK, Suscha A, Chan K, McLellan GJ, Pattnaik BR, Sorenson CM, Sheibani N
Scientific reports (2021) 111: 12670. 173 004 IHC; tested species: mouse
Increased Immunosignals of Collagen IV and Fibronectin Indicate Ischemic Consequences for the Neurovascular Matrix Adhesion Zone in Various Animal Models and Human Stroke Tissue.
Michalski D, Spielvogel E, Puchta J, Reimann W, Barthel H, Nitzsche B, Mages B, Jäger C, Martens H, Horn AKE, Schob S, et al.
Frontiers in physiology (2020) 11: 575598. 173 004 IHC; tested species: mouse,rat,sheep
Langat virus infection affects hippocampal neuron morphology and function in mice without disease signs.
Cornelius ADA, Hosseini S, Schreier S, Fritzsch D, Weichert L, Michaelsen-Preusse K, Fendt M, Kröger A
Journal of neuroinflammation (2020) 171: 278. 173 004 IHC; tested species: mouse
Molecular design of hypothalamus development.
Romanov RA, Tretiakov EO, Kastriti ME, Zupancic M, Häring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, et al.
Nature (2020) 5827811: 246-252. 173 004 IHC; tested species: mouse
Sustained Hypoxia Alters nTS Glutamatergic Signaling and Expression and Function of Excitatory Amino Acid Transporters.
Matott MP, Hasser EM, Kline DD
Neuroscience (2020) : . 173 004 IHC; tested species: mouse
Mechanically transformative electronics, sensors, and implantable devices.
Byun SH, Sim JY, Zhou Z, Lee J, Qazi R, Walicki MC, Parker KE, Haney MP, Choi SH, Shon A, Gereau GB, et al.
Science advances (2019) 511: eaay0418. 173 004 IHC; tested species: mouse
Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism.
Gong J, Szegő ÉM, Leonov A, Benito E, Becker S, Fischer A, Zweckstetter M, Outeiro T, Schneider A
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 173 004 IHC; tested species: mouse
Neuropathological findings suggestive for a stroke in an alpaca (Vicugna pacos).
Schöniger S, Schütze E, Michalski D, Puchta J, Kaiser M, Härtig W
Acta veterinaria Scandinavica (2019) 611: 1. 173 004 IHC
Reduced Smoothened level rescued Aβ-induced memory deficits and neuronal inflammation in animal models of Alzheimer's disease.
Ma W, Wu M, Zhou S, Tao Y, Xie Z, Zhong Y
Journal of genetics and genomics = Yi chuan xue bao (2018) : . 173 004 IHC; tested species: mouse
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.
Ogrodnik M, Zhu Y, Langhi LGP, Tchkonia T, Krüger P, Fielder E, Victorelli S, Ruswhandi RA, Giorgadze N, Pirtskhalava T, Podgorni O, et al.
Cell metabolism (2018) : . 173 004 IHC; tested species: mouse
Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia.
Hüttenrauch M, Ogorek I, Klafki H, Otto M, Stadelmann C, Weggen S, Wiltfang J, Wirths O
Acta neuropathologica communications (2018) 61: 108. 173 004 IHC; tested species: mouse
Hypoxia activates a neuropeptidergic pathway from the paraventricular nucleus of the hypothalamus to the nucleus tractus solitarii.
Ruyle BC, Klutho PJ, Baines CP, Heesch CM, Hasser EM
American journal of physiology. Regulatory, integrative and comparative physiology (2018) : . 173 004 IHC; tested species: rat
Radial glial elements in the cerebral cortex of the lesser hedgehog tenrec.
Mack AF, Künzle H, Lange M, Mages B, Reichenbach A, Härtig W
Brain structure & function (2018) : . 173 004 IHC
Tanycytes and a differential fatty acid metabolism in the hypothalamus.
Hofmann K, Lamberz C, Piotrowitz K, Offermann N, But D, Scheller A, Al-Amoudi A, Kuerschner L
Glia (2017) 652: 231-249. 173 004 IHC, WB; tested species: mouse
Delayed histochemical alterations within the neurovascular unit due to transient focal cerebral ischemia and experimental treatment with neurotrophic factors.
Michalski D, Pitsch R, Pillai DR, Mages B, Aleithe S, Grosche J, Martens H, Schlachetzki F, Härtig W
PloS one (2017) 124: e0174996. 173 004 IHC
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, et al.
Neuron (2017) 935: 1066-1081.e8. 173 004 IHC; tested species: human,mouse
Neurovascular Specifications in the Alzheimer-Like Brain of Mice Affected by Focal Cerebral Ischemia: Implications for Future Therapies.
Michalski D, Hofmann S, Pitsch R, Grosche J, Härtig W
Journal of Alzheimer's disease : JAD (2017) 592: 655-674. 173 004 IHC; tested species: mouse
Damaged Neocortical Perineuronal Nets Due to Experimental Focal Cerebral Ischemia in Mice, Rats and Sheep.
Härtig W, Mages B, Aleithe S, Nitzsche B, Altmann S, Barthel H, Krueger M, Michalski D
Frontiers in integrative neuroscience (2017) 11: 15. 173 004 IHC; tested species: mouse,rat,sheep
An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody.
Batiuk MY, de Vin F, Duqué SI, Li C, Saito T, Saido T, Fiers M, Belgard TG, Holt MG
The Journal of biological chemistry (2017) 29221: 8874-8891. 173 004 IHC; tested species: mouse
Excitatory amino acid transporters tonically restrain nTS synaptic and neuronal activity to modulate cardiorespiratory function.
Matott MP, Ruyle BC, Hasser EM, Kline DD
Journal of neurophysiology (2016) 1153: 1691-702. 173 004 IHC; tested species: rat
Dual roles of the adenosine A2a receptor in autoimmune neuroinflammation.
Ingwersen J, Wingerath B, Graf J, Lepka K, Hofrichter M, Schröter F, Wedekind F, Bauer A, Schrader J, Hartung HP, Prozorovski T, et al.
Journal of neuroinflammation (2016) 13: 48. 173 004 IHC
Immunohistochemical insights into Saffold virus infection of the brain of juvenile AG129 mice.
Tan SZ, Prabakaran M
Virology journal (2016) 131: 191. 173 004 IHC
Up-regulation of neurofilament light chains is associated with diminished immunoreactivities for MAP2 and tau after ischemic stroke in rodents and in a human case.
Härtig W, Krueger M, Hofmann S, Preißler H, Märkel M, Frydrychowicz C, Mueller WC, Bechmann I, Michalski D
Journal of chemical neuroanatomy (2016) 78: 140-148. 173 004 IHC
Relaxin increases sympathetic nerve activity and activates spinally projecting neurons in the paraventricular nucleus of nonpregnant, but not pregnant, rats.
Coldren KM, Brown R, Hasser EM, Heesch CM
American journal of physiology. Regulatory, integrative and comparative physiology (2015) 30912: R1553-68. 173 004 IHC; tested species: rat
Widespread expression of erythropoietin receptor in brain and its induction by injury.
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, et al.
Molecular medicine (Cambridge, Mass.) (2015) : . 173 004 IHC
Detection and Quantification of β-Amyloid, Pyroglutamyl Aβ, and Tau in Aged Canines.
Schmidt F, Boltze J, Jäger C, Hofmann S, Willems N, Seeger J, Härtig W, Stolzing A
Journal of neuropathology and experimental neurology (2015) 749: 912-23. 173 004 IHC
The capsaicin receptor TRPV1 as a novel modulator of neural precursor cell proliferation.
Stock K, Garthe A, de Almeida Sassi F, Glass R, Wolf SA, Kettenmann H
Stem cells (Dayton, Ohio) (2014) 3212: 3183-95. 173 004 IHC
Blood-brain barrier breakdown after embolic stroke in rats occurs without ultrastructural evidence for disrupting tight junctions.
Krueger M, Härtig W, Reichenbach A, Bechmann I, Michalski D
PloS one (2013) 82: e56419. 173 004 IHC
D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase.
Ehmsen JT, Ma TM, Sason H, Rosenberg D, Ogo T, Furuya S, Snyder SH, Wolosker H
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3330: 12464-9. 173 004 IHC
Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation.
Breunig JJ, Gate D, Levy R, Rodriguez J, Kim GB, Danielpour M, Svendsen CN, Town T
Neural development (2012) 7: 26. 173 004 IHC
Long-lasting neuronal loss following experimental focal cerebral ischemia is not affected by combined administration of tissue plasminogen activator and hyperbaric oxygen.
Hobohm C, Laignel F, Kacza J, Küppers-Tiedt L, Heindl M, Schneider D, Grosche J, Härtig W, Michalski D
Brain research (2011) 1417: 115-26. 173 004 IHC
Rapid Increases in proBDNF after Pilocarpine-Induced Status Epilepticus in Mice Are Associated with Reduced proBDNF Cleavage Machinery.
Thomas AX, Cruz Del Angel Y, Gonzalez MI, Carrel AJ, Carlsen J, Lam PM, Hempstead BL, Russek SJ, Brooks-Kayal AR
eNeuro () 31: . 173 004 IHC
Blood-Brain Barrier Leakage during Early Epileptogenesis Is Associated with Rapid Remodeling of the Neurovascular Unit.
Bankstahl M, Breuer H, Leiter I, Märkel M, Bascuñana P, Michalski D, Bengel FM, Löscher W, Meier M, Bankstahl JP, Härtig W, et al.
eNeuro () 53: . 173 004 IHC; tested species: rat
Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1.
Blumenreich S, Ben-Yashar DP, Shalit T, Kupervaser M, Milenkovic I, Joseph T, Futerman AH
Journal of neurochemistry (2024) 1681: 52-65. 173 004 IHC-P; tested species: mouse
Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease.
Marengo L, Armbrust F, Schoenherr C, Storck SE, Schmitt U, Zampar S, Wirths O, Altmeppen H, Glatzel M, Kaether C, Weggen S, et al.
Cellular and molecular life sciences : CMLS (2022) 793: 168. 173 004 IHC-P; tested species: mouse
SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?
Löhr M, Härtig W, Schulze A, Kroiß M, Sbiera S, Lapa C, Mages B, Strobel S, Hundt JE, Bohnert S, Kircher S, et al.
International journal of molecular sciences (2022) 237: . 173 004 IHC-P; tested species: human
Modulators of Neuroinflammation Have a Beneficial Effect in a Lafora Disease Mouse Model.
Mollá B, Heredia M, Sanz P
Molecular neurobiology (2021) 586: 2508-2522. 173 004 IHC-P; tested species: mouse
Innate immune response in neuronopathic forms of Gaucher disease confers resistance against viral-induced encephalitis.
Melamed S, Avraham R, Rothbard DE, Erez N, Israely T, Klausner Z, Futerman AH, Paran N, Vitner EB
Acta neuropathologica communications (2020) 81: 144. 173 004 IHC-P; tested species: mouse
Reactive Glia-Derived Neuroinflammation: a Novel Hallmark in Lafora Progressive Myoclonus Epilepsy That Progresses with Age.
Lahuerta M, Gonzalez D, Aguado C, Fathinajafabadi A, García-Giménez JL, Moreno-Estellés M, Romá-Mateo C, Knecht E, Pallardó FV, Sanz P
Molecular neurobiology (2019) : . 173 004 IHC-P; tested species: mouse
Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex.
Stamou M, Grodzki AC, van Oostrum M, Wollscheid B, Lein PJ
Journal of neuroinflammation (2018) 151: 7. 173 004 ICC, FACS; tested species: rat
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Background

Glial fibrillary acidic protein GFAP is a glial-specific member of the intermediate filament protein family. This group comprises cell type-specific filamentous proteins with similar structure and function as scaffold for cytoskeleton assembly and maintenance.
Frequently, neural stem cells also express GFAP. In addition many types of brain tumors, probably derived from astrocytic cells, heavily express GFAP. This protein is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and others.
Point-mutations in the GFAP gene have been correlated to Alexander disease, a fatal leukoencephalopathy that leads to the dysmyelination or demyelination of the central nervous system.
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