Cat. No.: 224 006
Amount: 50 µg
Price:
$380.00
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| Cat. No. 224 006 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to AA 39 to 67 from mouse GABA-A receptor γ2 (UniProt Id: P22723) |
| Reactivity |
Reacts with: mouse (P22723), rat (P18508). Weaker signal: zebrafish (E7FF94). Other species not tested yet. |
| Specificity | Specific for GABA-A receptor γ2. Does not discriminate between the L and S form. |
| Matching control protein/peptide | 224-0P |
| Remarks |
WB: GABA-A receptor gamma2 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples. |
| Data sheet | 224_006.pdf |
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Gamma-aminobutyric acid type A (GABA-A) receptors mediate the majority of inhibitory neurotransmission in the brain. These receptor proteins are ligand gated chloride ion channels and consist of a pentameric combination of different subunits (alpha, beta, gamma, delta, epsilon and rho). The resulting heterogenous population of GABA-A receptor subtypes are expressed throughout the brain with specific cellular and subcellular expression patterns.