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Home > Products > 358 103

EPOR antibody - 358 103

EPOR is the receptor for erythropoietin
Rabbit polyclonal purified antibody
Cat. No.: 358 103
Amount: 50 µg
Price: $375.00
Cat. No. 358 103 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 2000 gallery  
IP: yes
ICC: 1 : 1000 gallery  
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 273 to 508 from human EPOR (UniProt Id: P19235)
Reactivity Reacts with: human (P19235), mouse (P14753).
Other species not tested yet.
Data sheet 358_103.pdf

References for EPOR - 358 103

Widespread expression of erythropoietin receptor in brain and its induction by injury.
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, et al.
Molecular medicine (Cambridge, Mass.) (2015) : . 358 103 WB, IHC, IHC-P
Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus.
Hassouna I, Ott C, Wüstefeld L, Offen N, Neher RA, Mitkovski M, Winkler D, Sperling S, Fries L, Goebbels S, Vreja IC, et al.
Molecular psychiatry (2016) 2112: 1752-1767. 358 103 IHC
Widespread expression of erythropoietin receptor in brain and its induction by injury.
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, et al.
Molecular medicine (Cambridge, Mass.) (2015) : . 358 103 WB, IHC, IHC-P
Widespread expression of erythropoietin receptor in brain and its induction by injury.
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, et al.
Molecular medicine (Cambridge, Mass.) (2015) : . 358 103 WB, IHC, IHC-P
Cat. No.: 358 103
Amount: 50 µg
Price: $375.00
Widespread expression of erythropoietin receptor in brain and its induction by injury.
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, et al.
Molecular medicine (Cambridge, Mass.) (2015) : . 358 103 WB, IHC, IHC-P
Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus.
Hassouna I, Ott C, Wüstefeld L, Offen N, Neher RA, Mitkovski M, Winkler D, Sperling S, Fries L, Goebbels S, Vreja IC, et al.
Molecular psychiatry (2016) 2112: 1752-1767. 358 103 IHC
Widespread expression of erythropoietin receptor in brain and its induction by injury.
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, et al.
Molecular medicine (Cambridge, Mass.) (2015) : . 358 103 WB, IHC, IHC-P
Widespread expression of erythropoietin receptor in brain and its induction by injury.
Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, et al.
Molecular medicine (Cambridge, Mass.) (2015) : . 358 103 WB, IHC, IHC-P
WB
ICC
Background
The erythropoietin receptor EPOR mediates EPO-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes and triggers the JAK2/STAT5 signaling cascade.
EPO has also been shown to exert potent neuroprotective, neuroregenerative and procognitive functions suggesting EPOR expression in the brain.
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