Synaptic Systems - Cytohesin1

Cat. No.: 212 103

Amount: 50 µg

Price: $375.00

WB

Background

Cytohesins are a group of guanine nucleotide exchange factors (GEFs) that contain an N-terminal coil, a central Sec-7 and a C-terminal pleckstrin homology (ph) domain.
They control the activity of ADP-ribosylation factors (Arfs) and are involved in the control of vesicular transport and organization of the actin cytoskeleton.
Cytohesins have also been reported to bind to integrins, a diverse family of heterodimeric transmembrane adhesion receptors that are present on most vertebrate cell types. These proteins are known to be involved in cell-cell or cell-matrix interactions.

1 ) Li CC, Molecular biology of the cell (2007) 1811: 4420-37.
2 ) Dierks H, The Journal of biological chemistry (2001) 27640: 37472-81.
3 ) Ogasawara M, The Journal of biological chemistry (2000) 2755: 3221-30.
4 ) Betz SF, Proceedings of the National Academy of Sciences of the United States of America (1998) 9514: 7909-14.
5 ) Meacci E, Proceedings of the National Academy of Sciences of the United States of America (1997) 945: 1745-8.

Protocols

WB

Cat. No. 212 103	50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet
Immunogen	Recombinant protein corresponding to AA 1 to 66 from rat Cytohesin1 (UniProt Id: P97694)
Reactivity	Reacts with: rat (P97694), mouse (Q9QX11). Other species not tested yet.
Data sheet	212_103.pdf

Cytohesin1 antibody - 212 103