Cat. No.: 261 011
Amount: 100 µg
Price:
$415.00
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| Cat. No. 261 011 |
100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not recommended ICC: not recommended IHC: not recommended IHC-P: not tested yet |
| Clone | 161B11 |
| Subtype | IgG2a (κ light chain) |
| Immunogen | Recombinant protein corresponding to AA 1 to 471 from rat Collybistin (UniProt Id: Q9QX73) |
| Epitop |
AA 4 to 229 from rat Collybistin (UniProt Id: Q9QX73) |
| Reactivity |
Reacts with: rat (Q9QX73), mouse (Q3UTH8). Other species not tested yet. |
| Specificity | Specific for collybistin, immunogen present in all three described splice-variants. K.O. validated |
| Data sheet | 261_011.pdf |
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The GDP/GTP-exchange factor collybistin is composed of a dbl homology domain (DH) and a pleckstrin homology domain (PH) connected by a linker sequence. Three splice variants with different C-terminal regions have been described, so far.
Collybistin is supposed to be involved in the clustering of gephyrin, a scaffolding protein linking glycine and GABA receptors to microtubuli.