Cat. No.: 253 303
Amount: 50 µg
Price:
$375.00
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| Cat. No. 253 303 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 128 to 140 from mouse CNIH3 (UniProt Id: Q6ZWS4) |
| Reactivity |
Reacts with: rat (D0Q0Y7), mouse (Q6ZWS4). Other species not tested yet. |
| Specificity | Specific for CNIH 3; recognizes isoforms 1 and 2. |
| Data sheet | 253_303.pdf |
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Ligand gated cation channels of the AMPA/GLuA subtype interact with a family of proteins termed transmembrane AMPA-receptor regulatory proteins (TARPs). These proteins regulate the surface expression and the biophysical properties of GluAs.
A second protein family of 4 members referred to as cornichon 1-4 or CNIH 1-4 has been attributed similar properties in mammals. However it is still under discussion whether these proteins serve as chaperones, involved in the trafficking of EGFR ligands from the ER to Golgi like their homologes in yeast and Drosophila, or as GluA auxilliary subunits. For CNIH 3 three isoforms have been described.