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CNIH2 antibody - 253 203

CNIH2 is a GluA interacting protein
Rabbit polyclonal purified antibody
Cat. No.: 253 203
Amount: 50 µg
Price: $375.00
Cat. No. 253 203 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 107 to 121 from mouse CNIH2 (UniProt Id: O35089)
Reactivity Reacts with: rat (Q5BJU5), mouse (O35089).
Other species not tested yet.
Matching control protein/peptide 253-2P
Data sheet 253_203.pdf

References for CNIH2 - 253 203

Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.
Sultana A, Nakaya N, Dong L, Abu-Asab M, Qian H, Tomarev SI
Experimental neurology (2014) 261: 802-11. 253 203 WB
Cat. No.: 253 203
Amount: 50 µg
Price: $375.00
Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.
Sultana A, Nakaya N, Dong L, Abu-Asab M, Qian H, Tomarev SI
Experimental neurology (2014) 261: 802-11. 253 203 WB
Background

Ligand gated cation channels of the AMPA/GLuA subtype interact with a family of proteins termed transmembrane AMPA-receptor regulatory proteins (TARPs). These proteins regulate the surface expression and the biophysical properties of GluAs.
A second protein family of 4 members referred to as cornichon 1-4 or CNIH 1-4 has been attributed similar properties in mammals. However it is still under discussion whether these proteins serve as chaperones, involved in the trafficking of EGFR ligands from the ER to Golgi like their homologes in yeast and Drosophila, or as GluA auxilliary subunits. For CNIH 3 three isoforms have been described.