Claudin11 peptide - 241-0P

Claudin11 is an oligodendrocyte specific protein

control peptide

Cat. No.: 241-0P

Amount: 100 µg

Price: $105.00

Cat. No. 241-0P	100 µg peptide, lyophilized. For reconstitution add 100 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized!
Applications
Immunogen	Synthetic peptide corresponding to AA 188 to 207 from rat Claudin11 (UniProt Id: Q99P82)
Recommended dilution	Optimal concentrations should be determined by the end-user.
Matching antibodies	241 003
Remarks	This control peptide consists of the synthetic peptide (aa 188 - 207 in rat) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.
Data sheet	241-0p.pdf

Cat. No.: 241-0P

Amount: 100 µg

Price: $105.00

Background

Claudin 11, also known as Oligodendrocyte specific protein (OSP), is one of the most abundant components of CNS myelin where it locates to the interlamellar strands in myelin sheaths. To date more than 20 members of the claudin family have been identified. They are expressed in epithelial and endothelial cells in all tight junction bearing tissues. Claudins share a common transmembrane topology with 4 transmembrane spanning domains and two extracellular loops.

1 ) Devaux J et al., J. Cell Biol. (2008)
2 ) Kitajiri S et al., J. Cell. Sci. (2004)
3 ) Tiwari-Woodruff SK et al., J. Cell Biol. (2001)
4 ) Bronstein JM et al., J. Neurosci. Res. (2000)
5 ) Morita K et al., J. Cell Biol. (1999)
6 ) Bronstein JM et al., J. Neurosci. Res. (1997)

Protocols

OTHER

Preadsorbtion

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