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Clathrin light chain antibody - 113 004

Clathrin light chain is a small clathrin coat subunit involved in endocytosis
Guinea pig polyclonal antiserum
Cat. No.: 113 004
Amount: 100 µl
Price: $365.00
Cat. No. 113 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 156 to 173 from rat Clathrin light chainB (UniProt Id: P08082)
Reactivity Reacts with: rat, mouse.
Other species not tested yet.
Specificity Specific for both neuronal light chains, does not cross-react with the non-neuronal variants.
Matching control protein/peptide 113-0P
Data sheet 113_004.pdf

References for Clathrin light chain - 113 004

The actin-spectrin submembrane scaffold restricts endocytosis along proximal axons.
Wernert F, Moparthi SB, Pelletier F, Lainé J, Simons E, Moulay G, Rueda F, Jullien N, Benkhelifa-Ziyyat S, Papandréou MJ, Leterrier C, et al.
Science (New York, N.Y.) (2024) 3856711: eado2032. 113 004 IHC; tested species: rat
Cat. No.: 113 004
Amount: 100 µl
Price: $365.00
The actin-spectrin submembrane scaffold restricts endocytosis along proximal axons.
Wernert F, Moparthi SB, Pelletier F, Lainé J, Simons E, Moulay G, Rueda F, Jullien N, Benkhelifa-Ziyyat S, Papandréou MJ, Leterrier C, et al.
Science (New York, N.Y.) (2024) 3856711: eado2032. 113 004 IHC; tested species: rat
Background
Clathrin consists of heavy chains and light chains that co-assemble to triskelions. The light chains are differentially spliced, with neurons expressing a special variant that is not detectable elsewhere. The neuron-specific light chains are enriched in synaptic nerve terminals where they participate in synaptic vesicle endocytosis.