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Home > Products > 365 003

Ca2+ channel L-type alpha-1F antibody - 365 003

Rabbit polyclonal purified antibody
Cat. No.: 365 003
Amount: 50 µg
Price: $375.00
Cat. No. 365 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: 1 : 1000 gallery  
Immunogen Recombinant protein corresponding to AA 1667 to 1985 from mouse Cav1.4 (UniProt Id: Q7TNI3)
Reactivity Reacts with: mouse (Q9JIS7).
Other species not tested yet.
Specificity Specific for the Ca2+ channel α-1F subunit.
Data sheet 365_003.pdf

References for Ca2+ channel L-type alpha-1F - 365 003

The first synapse in vision in the aging mouse retina.
Gierke K, Lux UT, Regus-Leidig H, Brandstätter JH
Frontiers in cellular neuroscience (2023) 17: 1291054. 365 003 IHC; tested species: mouse
Genetic disruption of bassoon in two mutant mouse lines causes divergent retinal phenotypes.
Ryl M, Urbasik A, Gierke K, Babai N, Joachimsthaler A, Feigenspan A, Frischknecht R, Stallwitz N, Fejtová A, Kremers J, von Wittgenstein J, et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2021) 355: e21520. 365 003 IHC; tested species: mouse
The absence of functional bassoon at cone photoreceptor ribbon synapses affects signal transmission at Off cone bipolar cell contacts in mouse retina.
Babai N, von Wittgenstein J, Gierke K, Brandstätter JH, Feigenspan A
Acta physiologica (Oxford, England) (2021) 2313: e13584. 365 003 IHC; tested species: mouse
Cat. No.: 365 003
Amount: 50 µg
Price: $375.00
The first synapse in vision in the aging mouse retina.
Gierke K, Lux UT, Regus-Leidig H, Brandstätter JH
Frontiers in cellular neuroscience (2023) 17: 1291054. 365 003 IHC; tested species: mouse
Genetic disruption of bassoon in two mutant mouse lines causes divergent retinal phenotypes.
Ryl M, Urbasik A, Gierke K, Babai N, Joachimsthaler A, Feigenspan A, Frischknecht R, Stallwitz N, Fejtová A, Kremers J, von Wittgenstein J, et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2021) 355: e21520. 365 003 IHC; tested species: mouse
The absence of functional bassoon at cone photoreceptor ribbon synapses affects signal transmission at Off cone bipolar cell contacts in mouse retina.
Babai N, von Wittgenstein J, Gierke K, Brandstätter JH, Feigenspan A
Acta physiologica (Oxford, England) (2021) 2313: e13584. 365 003 IHC; tested species: mouse
IHC
IHC-P
Background
Voltage gated calcium channels (VGCCs), also referred to as voltage sensitive calcium channels (VSCCs), are present in most excitable cells. They mediate the influx of Ca2+ ions into the cell and trigger the release of neurotransmitters or hormons but are also involved in other calcium dependent processes like metabolism, cell proliferation and cell death.
VGCCs are composed of four subunits (α-1, α-2, β and δ) in a 1:1:1:1 ratio. The α-1F subunit occurs in VGCCs of the L-type expressed in the retina.