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Home > Products > 343 008

c-Myc antibody - 343 008

c-Myc is a protein involved in the control of cell proliferation
Rabbit monoclonal recombinant IgG
Cat. No.: 343 008
Amount: 100 µg
Price: $415.00
Cat. No. 343 008 100 µg purified recombinant IgG, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: yes
IHC-P: yes
Clone Rb9E10
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to AA 408 to 432 from human c-Myc (UniProt Id: P01106)
Epitop EQKLISEEDL
Reactivity Reacts with: human (P01106).
Other species not tested yet.
Remarks

This antibody is a chimeric antibody based on the well known monoclonal mouse antibody 9E10. The constant regions of the heavy and light chains have been replaced with rabbit specific sequences. The antibody can therefore be used with standard anti-rabbit secondary reagents. It also carries a Strep-tag at the C-terminus of the heavy chain.The antibody has been expressed in mammalian cells.
Data sheet 343_008.pdf

References for c-Myc - 343 008

Novel Functional Properties of Missense Mutations in the Glycine Receptor β Subunit in Startle Disease.
Piro I, Eckes AL, Kasaragod VB, Sommer C, Harvey RJ, Schaefer N, Villmann C
Frontiers in molecular neuroscience (2021) 14: 745275. 343 008 ICC; tested species: mouse
The Rab5 activator RME-6 is required for amyloid precursor protein endocytosis depending on the YTSI motif.
Eggert S, Gruebl T, Rajender R, Rupp C, Sander B, Heesch A, Zimmermann M, Hoepfner S, Zentgraf H, Kins S
Cellular and molecular life sciences : CMLS (2020) : . 343 008 ICC; tested species: human
Cat. No.: 343 008
Amount: 100 µg
Price: $415.00
Novel Functional Properties of Missense Mutations in the Glycine Receptor β Subunit in Startle Disease.
Piro I, Eckes AL, Kasaragod VB, Sommer C, Harvey RJ, Schaefer N, Villmann C
Frontiers in molecular neuroscience (2021) 14: 745275. 343 008 ICC; tested species: mouse
The Rab5 activator RME-6 is required for amyloid precursor protein endocytosis depending on the YTSI motif.
Eggert S, Gruebl T, Rajender R, Rupp C, Sander B, Heesch A, Zimmermann M, Hoepfner S, Zentgraf H, Kins S
Cellular and molecular life sciences : CMLS (2020) : . 343 008 ICC; tested species: human
WB
ICC
Background
The c-Myc oncogene (p62 c-Myc) is a nuclear protein that is involved in the control of normal cellular proliferation and differentiation. Deregulated expression of c-Myc induces apoptosis in different cell types.
The C-terminal c-Myc amino acids are widely used in combination with eukaryotic expression vectors encoding proteins with c-Myc epitope tag.
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