Cat. No.: 322 205
Amount: 50 µg
Price:
$460.00
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| Cat. No. 322 205 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to AA 917 to 940 from rat GABABR2 (UniProt Id: O88871) |
| Reactivity |
Reacts with: rat (O88871), mouse (Q80T41). Other species not tested yet. |
| Specificity | K.O. validated PubMed: 26691831 |
| Data sheet | 322_205.pdf |
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Metabotropic g-aminobutyric acid type B receptors (GABABRs) are involved in the modulation of synaptic transmission and activity of cerebellar and thalamic neurons.
In contrast to the ionotrophic GABA-A receptors they are linked to G-proteins underlying the slow inhibitory postsynaptic potentials.
GABABR 1 and GABABR 2 have been shown to form heterodimers.