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Home > Products > 322 102

GABABR1 antibody - 322 102

GABABR1 is a metabotropic GABA receptor
Rabbit polyclonal antiserum
Cat. No.: 322 102
Amount: 200 µl
Price: $355.00
Cat. No. 322 102 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 200 up to 1 : 500
IHC-P: not tested yet

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.

Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen Recombinant protein corresponding to AA 903 to 960 from mouse GabaBR1 (UniProt Id: Q9WV18)
Reactivity Reacts with: rat, mouse (Q9WV18).
Other species not tested yet.
Specificity Detects both isoforms GABABR 1a and 1b.
Data sheet 322_102.pdf

References for GABABR1 - 322 102

Inhibitory control in neuronal networks relies on the extracellular matrix integrity.
Dzyubenko E, Fleischer M, Manrique-Castano D, Borbor M, Kleinschnitz C, Faissner A, Hermann DM
Cellular and molecular life sciences : CMLS (2021) 7814: 5647-5663. 322 102 WB, IHC; tested species: mouse
Inhibitory control in neuronal networks relies on the extracellular matrix integrity.
Dzyubenko E, Fleischer M, Manrique-Castano D, Borbor M, Kleinschnitz C, Faissner A, Hermann DM
Cellular and molecular life sciences : CMLS (2021) 7814: 5647-5663. 322 102 WB, IHC; tested species: mouse
Cat. No.: 322 102
Amount: 200 µl
Price: $355.00
Inhibitory control in neuronal networks relies on the extracellular matrix integrity.
Dzyubenko E, Fleischer M, Manrique-Castano D, Borbor M, Kleinschnitz C, Faissner A, Hermann DM
Cellular and molecular life sciences : CMLS (2021) 7814: 5647-5663. 322 102 WB, IHC; tested species: mouse
Inhibitory control in neuronal networks relies on the extracellular matrix integrity.
Dzyubenko E, Fleischer M, Manrique-Castano D, Borbor M, Kleinschnitz C, Faissner A, Hermann DM
Cellular and molecular life sciences : CMLS (2021) 7814: 5647-5663. 322 102 WB, IHC; tested species: mouse
WB
ICC
Background

Metabotropic g-aminobutyric acid type B receptors (GABABRs) are involved in the modulation of synaptic transmission and activity of cerebellar and thalamic neurons.
In contrast to the ionotrophic GABA-A receptors they are linked to G-proteins underlying the slow inhibitory postsynaptic potentials.
GABABR 1 and GABABR 2 have been shown to form heterodimers.