Cat. No.: 182 105
Amount: 50 µg
Price:
$465.00
|
|
|
| Cat. No. 182 105 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 836 to 883 from rat GluA2 (UniProt Id: P19491) |
| Reactivity |
Reacts with: rat (P19491), mouse. Other species not tested yet. |
| Specificity | Some cross reactivity to GluA 3. |
| Matching control protein/peptide | 182-1P |
| Data sheet | 182_105.pdf |
|
|
Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN and kainate/GluK receptors (KARs). mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins.
Glutamate receptors of the AMPA subtype are monovalent cation channels and are composed of the four AMPA subunits GluA 1, GluA 2, GluA 3, and GluA 4.