Aldh1L1 peptide - 278-0P

Aldh1L1 is a folate metabolic enzyme

control peptide

Cat. No.: 278-0P

Amount: 100 µg

Price: $105.00

Cat. No. 278-0P	100 µg peptide, lyophilized. For reconstitution add 100 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized!
Applications
Immunogen	Synthetic peptide corresponding to AA 250 to 269 from rat Aldh1L1 (UniProt Id: P28037)
Recommended dilution	Optimal concentrations should be determined by the end-user.
Matching antibodies	278 003
Remarks	This control peptide consists of the synthetic peptide (aa 250-269 of rat Aldh1L1) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.
Data sheet	278-0p.pdf

Cat. No.: 278-0P

Amount: 100 µg

Price: $105.00

Background

Aldehyde dehydrogenase family 1 member L1 (Aldh1L1), also known as 10-formyltetrahydrofolate dehydrogenase (FDH) is a cytosolic enzyme involved in folate metabolism. It has been shown to be involved in the regulation of cell proliferation and is downregulated in malignant human tumors and cancer cell lines.
Aldh1L1 is highly expressed in several cell-types like hepatocytes and astrocytes.

1 ) Oleinik NV et al., Genes Cancer (2011)
2 ) Yang Y et al., Glia (2011)
3 ) Rodriguez FJ et al., J. Neuropathol. Exp. Neurol. (2008)
4 ) Cahoy JD et al., J. Neurosci. (2008)
5 ) Anthony TE et al., J. Comp. Neurol. (2007)
6 ) Krupenko SA et al., Cell Growth Differ. (2002)

Protocols

OTHER

Preadsorbtion

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