Cat. No.: 329 002
Amount: 200 µl
Price:
$355.00
Cat. No. 329 002 |
200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
Applications |
Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IP: not tested yet Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.', $event)" style="cursor: help;">ICC: not tested yet Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IHC: not recommended Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.', $event)" style="cursor: help;">IHC-P: not tested yet |
Immunogen | Synthetic peptide corresponding to AA 1 to 26 from mouse ABP1 (UniProt Id: Q62418) |
Reactivity |
Reacts with: rat (Q9JHL4), mouse (Q62418). Other species not tested yet. |
Specificity | Specific for ABP1. |
Data sheet | 329_002.pdf |
The Actin-binding protein 1 (ABP1) also known as SH3P7, Dbnl or Debrin-like protein binds to actin filaments especially at sites that represent cellular growth.
In neurons ABP1 has been shown to interact with the scaffoliding PSD proteins Shank2 and Shank3. This suggests an involvement in activity-dependent reorganizations of the cortical actin cytoskeleton necessary for synaptic plasticity.