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CD19 antibody - HS-439 017

CD19 is a B-lymphocyte antigen
Rat monoclonal purified IgG
Cat. No.: HS-439 017
Amount: 100 µg
Price: $415.00
Cat. No. HS-439 017 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 250 gallery  
ICCgallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: 1 : 100 gallery  
Clone 26D7E5
Subtype IgG2b (κ light chain)
Epitop Epitop: AA 527 to 547 from mouse CD19 (UniProt Id: P25918)
Reactivity Reacts with: mouse (P25918).
No signal: human (P15391).
Other species not tested yet.
Specificity Specific for mouse CD19 without cross-reactivity to human CD19
Data sheet hs-439_017.pdf
Important information
This product belongs to the HistoSure product line of antibodies developed for and extensively tested in FFPE tissues.
For more information please visit our HistoSure brand website.
Cat. No.: HS-439 017
Quantity: 100 µg
Price: $415.00
Background

CD19 (Cluster of Differentiation 19) is a B cell-restricted signal-transduction molecule that plays an important role in the regulation of development, activation, and differentiation of B-lymphocytes. CD19 is considered as a biomarker for B-cells because of its continued expression from very early B cell development stages. It is evident already on pro-B cells and on all later B cell stages, until plasma cell terminal differentiation, when its expression is lost. In complex with CD21, CD81 and CD225, CD19 functions as a dominant signaling receptor on the surface of mature B cells. CD19-deficient mice show defects in initial B-cell activation by T-cell-dependent antigens and in the maturation and/or selection of the activated cells into the memory compartment.