Tailor-made Antibodies
and Tools for Life Science
my list | quick order | cart
0
|
login
Home > Products > HS-315 111-S

Calreticulin mutation antibody CAL2 - HS-315 111-S

This neoepitope is present in all NPM associated Calreticulin mutations

 

The format of this antibody has been changed from µl to µg. The increased antibody amount allows a 20 fold

higher dilution, which significantly reduces the costs per immunostaining.

Mouse monoclonal purified IgG
Cat. No.: HS-315 111-S
Amount: 50 µg
Price: $255.00
Cat. No. HS-315 111-S 50 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: 1 : 400 up to 1 : 800 gallery  
Clone CAL2
Subtype IgG2a (λ light chain)
Immunogen Recombinant protein corresponding to the neoepitope in human mutated calreticulin (UniProt Id: P27797)
Reactivity Reacts with: human (P27797).
Other species not tested yet.
Specificity Specific for the neoepitope in mutated Calreticulin.
Data sheet hs-315_111-s.pdf
Important information
This product belongs to the HistoSure product line of antibodies developed for and extensively tested in FFPE tissues.
For more information please visit our HistoSure brand website.

References for Calreticulin mutation - HS-315 111-S

Calreticulin mutation specific CAL2 immunohistochemistry accurately identifies rare calreticulin mutations in myeloproliferative neoplasms.
Mózes R, Gángó A, Sulák A, Vida L, Reiniger L, Timár B, Krenács T, Alizadeh H, Masszi T, Gaál-Weisinger J, Demeter J, et al.
Pathology (2018) : . HS-315 111-S IHC-P; tested species: human
A new monoclonal antibody (CAL2) detects CALRETICULIN mutations in formalin-fixed and paraffin-embedded bone marrow biopsies.
Stein H, Bob R, Dürkop H, Erck C, Kämpfe D, Kvasnicka HM, Martens H, Roth A, Streubel A
Leukemia (2016) 301: 131-5. HS-315 111-S IHC-P; tested species: human
CAL2 Immunohistochemical Staining Accurately Identifies CALR Mutations in Myeloproliferative Neoplasms.
Nomani L, Bodo J, Zhao X, Durkin L, Loghavi S, Hsi ED
American journal of clinical pathology (2016) 1464: 431-8. HS-315 111-S IHC-P; tested species: human
Mutation specific immunohistochemistry is highly specific for the presence of calreticulin mutations in myeloproliferative neoplasms.
Andrici J, Farzin M, Clarkson A, Sioson L, Sheen A, Watson N, Toon CW, Koleth M, Stevenson W, Gill AJ
Pathology (2016) 484: 319-24. HS-315 111-S IHC-P; tested species: human
Cat. No.: HS-315 111-S
Amount: 50 µg
Price: $255.00
IHC-P
Other products for this target