Cat. No.: 505 005
Amount: 50 µg
Price:
$460.00
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| Cat. No. 505 005 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to residues near the carboxy terminus of mouse Tight junction protein ZO-3 (UniProt Id: Q9QXY1) |
| Reactivity |
Reacts with: mouse (Q9QXY1), rat (D3Z8G7), dog (O62683). Other species not tested yet. |
| Remarks |
ICC: Methanol fixation is recommended |
| Data sheet | 505_005.pdf |
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ZO-3 is a 130 kDa protein identified by co-immunoprecipitation with ZO-1 from Madin-Darby canine kidney (MDCK) cells. (1)
ZO-3 is a member of the membrane-associated guanylate kinase-like protein (MAGUK) family associated with intracellular junctions. (2)
The zona occludens proteins ZO-1, -2 and -3 (also known as TJP1, 2 and 3) are peripheral membrane adaptor proteins that link transmembrane junction proteins such as occludin and claudin to the actin cytoskeleton (3).