|Cat. No. 461 003||50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.|
WB: 1 : 1000 (see remarks) gallery
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
|Immunogen||Synthetic peptide corresponding to AA 27 to 46 from rat Tmem22 (UniProt Id: Q5M7A3)|
Reacts with: rat (Q5M7A3), mouse (D3YVE8).
Other species not tested yet.
|Specificity||Specific for TMEM22|
WB: TMEM22 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.
Transmembrane protein 22, TMEM22 contains 10 putative transmembrane domains and has been shown to be upregulated in renal cell carcinoma (RCC). Together with its suggested interaction partner Rab37 It may be involved in the regulation of cell proliferation (1). TMEM22 is also expressed in brain, where it is enriched in synaptic vesicles.