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DNAL 1 - 433 004

A component of outer dynein arms
Polyclonal Guinea pig antiserum
Cat. No.: 433 004
Amount: 100 µl
Price: 350.00 €
Cat. No. 433 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 2000 AP staining gallery  
IP: not tested yet
ICC: not recommended
IHC: 1 : 500 up to 1 : 1000 (see remarks) gallery  
IHC-P/FFPE: 1 : 1000 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 190 from mouse Dnal1 (UniProt Id: Q05A62)
Reactivity Reacts with: mouse (Q05A62), rat (A0A096MJZ0).
Other species not tested yet.
Specificity Specific for DNAL 1
Remarks

IHC: Antigen retrieval (10mM citrate, pH 6.0, overnight at 60°C) is recommended.

Data sheet 433_004.pdf
Cat. No.: 433 004
Quantity: 100 µl
Price: 350.00 €
Background

DNAL 1, the Dynein light chain 1, also known as MGC12435 or C14orf168, is an axonemal protein found in the outer dynein arms complex. DNAL 1 uses ATP to provide the force for movement of motile cilia or flagella. DNAL 1 interacts directly with DNAH 5 and is expressed in the testis and other tissues containing motile cilia. Alternate splicing results in multiple transcript variants.