Tailor-made Antibodies
and Tools for Life Science
Home|||||Technical Support

Aquaporin 4 antibody - 429 004

Aquaporin4 is a water-specific channel in the blood brain barrier
Guinea pig polyclonal antiserum
Cat. No.: 429 004
Amount: 100 µl
Price: $350.00
Cat. No. 429 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 5000 up to 1 : 10000 AP staining gallery  
IP: yes
ICC: 1 : 1000 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P: 1 : 1000 gallery  
Immunogen Recombinant protein corresponding to AA 249 to 323 from mouse Aquaporin-4 isoform 2 (UniProt Id: P55088-1)
Reactivity Reacts with: rat (P47863), mouse (P55088-1).
Other species not tested yet.
Specificity Specific for Aquaporin- 4, detects all described isoforms.
Matching control protein/peptide 429-0P
Data sheet 429_004.pdf

References for Aquaporin 4 - 429 004

The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner.
Tóth K, Lénárt N, Berki P, Fekete R, Szabadits E, Pósfai B, Cserép C, Alatshan A, Benkő S, Kiss D, Hübner CA, et al.
PLoS biology (2022) 201: e3001526. 429 004 IHC; tested species: mouse
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions.
Császár E, Lénárt N, Cserép C, Környei Z, Fekete R, Pósfai B, Balázsfi D, Hangya B, Schwarcz AD, Szabadits E, Szöllősi D, et al.
The Journal of experimental medicine (2022) 2193: . 429 004 IHC; tested species: mouse
Update on Perineuronal Net Staining With Wisteria floribunda Agglutinin (WFA).
Härtig W, Meinicke A, Michalski D, Schob S, Jäger C
Frontiers in integrative neuroscience (2022) 16: 851988. 429 004 IHC; tested species: mouse
Cat. No.: 429 004
Amount: 100 µl
Price: $350.00
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner.
Tóth K, Lénárt N, Berki P, Fekete R, Szabadits E, Pósfai B, Cserép C, Alatshan A, Benkő S, Kiss D, Hübner CA, et al.
PLoS biology (2022) 201: e3001526. 429 004 IHC; tested species: mouse
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions.
Császár E, Lénárt N, Cserép C, Környei Z, Fekete R, Pósfai B, Balázsfi D, Hangya B, Schwarcz AD, Szabadits E, Szöllősi D, et al.
The Journal of experimental medicine (2022) 2193: . 429 004 IHC; tested species: mouse
Update on Perineuronal Net Staining With Wisteria floribunda Agglutinin (WFA).
Härtig W, Meinicke A, Michalski D, Schob S, Jäger C
Frontiers in integrative neuroscience (2022) 16: 851988. 429 004 IHC; tested species: mouse
Background

Aquaporin 4, or AQP4, also known as Mercurial-insensitive water channel (MIWC), is a member of the aquaporin water channel family. This osmoreceptor regulates body water balance and mediates water flow within the central nervous system.