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Home > Products > 400 102

TMEM119 antibody human specific - 400 102

TMEM119 is a microglia specific transmembrane protein
Rabbit polyclonal antiserum
Cat. No.: 400 102
Amount: 200 µl
Price: $355.00
Cat. No. 400 102 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P: 1 : 1000 gallery  
Immunogen Recombinant protein corresponding to AA 194 to 283 from human TMEM119 (UniProt Id: Q4V9L6)
Reactivity Reacts with: human (Q4V9L6).
Other species not tested yet.
Remarks

This antibody is recommended for material from human only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely.
Data sheet 400_102.pdf

References for TMEM119 - 400 102

A modified protocol for isolation of retinal microglia from the pig.
Zhang Y, Erhard AL, Plagemann T, Eter N, Heiduschka P
Experimental eye research (2021) 207: 108584. 400 102 ICC; tested species: pig
Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia.
Sepulveda-Falla D, Sanchez JS, Almeida MC, Boassa D, Acosta-Uribe J, Vila-Castelar C, Ramirez-Gomez L, Baena A, Aguillon D, Villalba-Moreno ND, Littau JL, et al.
Acta neuropathologica (2022) 1443: 589-601. 400 102 IHC; tested species: human
Cat. No.: 400 102
Amount: 200 µl
Price: $355.00
A modified protocol for isolation of retinal microglia from the pig.
Zhang Y, Erhard AL, Plagemann T, Eter N, Heiduschka P
Experimental eye research (2021) 207: 108584. 400 102 ICC; tested species: pig
Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia.
Sepulveda-Falla D, Sanchez JS, Almeida MC, Boassa D, Acosta-Uribe J, Vila-Castelar C, Ramirez-Gomez L, Baena A, Aguillon D, Villalba-Moreno ND, Littau JL, et al.
Acta neuropathologica (2022) 1443: 589-601. 400 102 IHC; tested species: human
IHC-P
Background
Microglia are resident myeloid cells of the central nervous system (CNS). They are ontogenetically and functionally distinct from monocyte-derived macrophages that infiltrate the CNS under pathological conditions. Transmembrane protein 119 (TMEM 119) is a single-pass type I membrane protein that has been identified as a useful, highly selective microglia marker protein.
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