Synaptic Systems

Cat. No.: 400 004

Amount: 100 µl

Price: $375.00

Cat. No. 400 004	100 µl antiserum, lyophilized. For reconstitution add 100 µl H₂O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: not tested yet IP: not tested yet ICC: not tested yet IHC: 1 : 500 gallery IHC-P: 1 : 500 gallery IHC-Fr: 1 : 100 (see remarks)
Immunogen	Recombinant protein corresponding to the C-terminal region of mouse TMEM119 (UniProt Id: Q8R138)
Reactivity	Reacts with: mouse (Q8R138). Other species not tested yet.
Specificity	K.D. validated PubMed: 37635351
Remarks	This antibody is recommended for mouse only. Due to significant differences of TMEM 119 among species, cross-reactivity is unlikely. IHC-Fr: 5 min MeOH and PFA fixation are possible.
Data sheet	400_004.pdf

References for TMEM119 - 400 004

Microglial reprogramming enhances antitumor immunity and immunotherapy response in melanoma brain metastases.
Rodriguez-Baena FJ, Marquez-Galera A, Ballesteros-Martinez P, Castillo A, Diaz E, Moreno-Bueno G, Lopez-Atalaya JP, Sanchez-Laorden B
Cancer cell (2025) : . 400 004 IHC; tested species: mouse

Transcriptome and proteome profiling reveals TREM2-dependent and -independent glial response and metabolic perturbation in an Alzheimer's mouse model.
Lin D, Kaye S, Chen M, Lyanna A, Ye L, Hammond LA, Gao J
The Journal of biological chemistry (2024) : 107874. 400 004 IHC; tested species: mouse

Repopulated microglia after pharmacological depletion decrease dendritic spine density in adult mouse brain.
Wickel J, Chung HY, Ceanga M, von Stackelberg N, Hahn N, Candemir Ö, Baade-Büttner C, Mein N, Tomasini P, Woldeyesus DM, Andreas N, et al.
Glia (2024) : . 400 004 IHC; tested species: mouse

Human-induced pluripotent stem cell-derived microglia integrate into mouse retina and recapitulate features of endogenous microglia.
Ma W, Zhao L, Xu B, Fariss RN, Redmond TM, Zou J, Wong WT, Li W
eLife (2024) 12: . 400 004 IHC; tested species: mouse

CCR3 plays a role in murine age-related cognitive changes and T-cell infiltration into the brain.
Rege SV, Teichert A, Masumi J, Dhande OS, Harish R, Higgins BW, Lopez Y, Akrapongpisak L, Hackbart H, Caryotakis S, Leone DP, et al.
Communications biology (2023) 61: 292. 400 004 IHC; tested species: mouse

A comparative analysis of microglial inducible Cre lines.
Faust TE, Feinberg PA, O'Connor C, Kawaguchi R, Chan A, Strasburger H, Frosch M, Boyle MA, Masuda T, Amann L, Knobeloch KP, et al.
Cell reports (2023) 429: 113031. 400 004 IHC; KD verified; tested species: mouse

Local translation in microglial processes is required for efficient phagocytosis.
Vasek MJ, Mueller SM, Fass SB, Deajon-Jackson JD, Liu Y, Crosby HW, Koester SK, Yi J, Li Q, Dougherty JD
Nature neuroscience (2023) 267: 1185-1195. 400 004 IHC; tested species: mouse

URMC-099 prophylaxis prevents hippocampal vascular vulnerability and synaptic damage in an orthopedic model of delirium superimposed on dementia.
Miller-Rhodes P, Li H, Velagapudi R, Chiang W, Terrando N, Gelbard HA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2022) 366: e22343. 400 004 IHC; tested species: mouse

Myeloid Cells in the Mouse Retina and Uveal Tract Respond Differently to Systemic Inflammatory Stimuli.
Dando SJ, Kazanis R, McMenamin PG
Investigative ophthalmology & visual science (2021) 6210: 10. 400 004 IHC; tested species: mouse

The Mononuclear Phagocyte System of the Rat.
Hume DA, Caruso M, Keshvari S, Patkar OL, Sehgal A, Bush SJ, Summers KM, Pridans C, Irvine KM
Journal of immunology (Baltimore, Md. : 1950) (2021) 20610: 2251-2263. 400 004 IHC; tested species: rat

Cat. No.: 400 004

Amount: 100 µl

Price: $375.00

IHC

IHC-P

Background

Protocols

Other products for this target

TMEM119 antibody mouse specific - 400 004 K.D.

References for TMEM119 - 400 004