Cat. No.: 395 103
Amount: 50 µg
Price:
$375.00
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| Cat. No. 395 103 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Synthetic peptide corresponding to residues surrounding AA 990 of mouse Taok2 β (UniProt Id: Q6ZQ29-2) |
| Reactivity |
Reacts with: mouse (Q6ZQ29-2), rat (Q9JLS3-2). Other species not tested yet. |
| Specificity | K.O. validated |
| Data sheet | 395_103.pdf |
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The serine/threonine-protein kinase Taok 2 or TAO 2 plays a role in membrane blebbing and the formation of apoptotic bodies. Taok 2 is involved in the MAPK14/p38 MAPK stress-activated MAPK cascade. It may also affect the cytoskeletal organization and stability, the dendritic formation, and the osmotic stress-MAPK8 pathway. There are two isoforms, Taok 2α and Taok 2β, only the latter is required for PCDH8 endocytosis and CDH2 cointernalization.