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Ankyrin G - 386 004

A membrane-cytoskeleton linker
Polyclonal Guinea pig antiserum
Cat. No.: 386 004
Amount: 100 µl
Price: $350.00
Cat. No. 386 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 1784 to 1961 from mouse AnkyrinG (UniProt Id: G5E8K5-1)
Reactivity Reacts with: rat (O70511-1), mouse (G5E8K5-1).
Other species not tested yet.
Specificity Specific for Ankyrin G; detects all described splice variants. K.D. PubMed: 31727776
Data sheet 386_004.pdf

References for Ankyrin G - 386 004

NuMA1 promotes axon initial segment assembly through inhibition of endocytosis.
Torii T, Ogawa Y, Liu CH, Ho TS, Hamdan H, Wang CC, Oses-Prieto JA, Burlingame AL, Rasband MN
The Journal of cell biology (2020) 2192: . 386 004 ICC; KD verified; tested species: mouse
TRIM46 organizes microtubule fasciculation in the axon initial segment.
Harterink M, Vocking K, Pan X, Soriano Jerez EM, Slenders L, Fréal A, Tas RP, van de Wetering WJ, Timmer K, Motshagen J, van Beuningen SFB, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 386 004 ICC; tested species: rat
Granule Cell Ensembles in Mouse Dentate Gyrus Rapidly Upregulate the Plasticity-Related Protein Synaptopodin after Exploration Behavior.
Paul MH, Choi M, Schlaudraff J, Deller T, Del Turco D
Cerebral cortex (New York, N.Y. : 1991) (2019) : . 386 004 IHC; tested species: mouse
Cat. No.: 386 004
Quantity: 100 µl
Price: $350.00
NuMA1 promotes axon initial segment assembly through inhibition of endocytosis.
Torii T, Ogawa Y, Liu CH, Ho TS, Hamdan H, Wang CC, Oses-Prieto JA, Burlingame AL, Rasband MN
The Journal of cell biology (2020) 2192: . 386 004 ICC; KD verified; tested species: mouse
TRIM46 organizes microtubule fasciculation in the axon initial segment.
Harterink M, Vocking K, Pan X, Soriano Jerez EM, Slenders L, Fréal A, Tas RP, van de Wetering WJ, Timmer K, Motshagen J, van Beuningen SFB, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 386 004 ICC; tested species: rat
Granule Cell Ensembles in Mouse Dentate Gyrus Rapidly Upregulate the Plasticity-Related Protein Synaptopodin after Exploration Behavior.
Paul MH, Choi M, Schlaudraff J, Deller T, Del Turco D
Cerebral cortex (New York, N.Y. : 1991) (2019) : . 386 004 IHC; tested species: mouse
Background
Ankyrin G is a membrane-cytoskeleton linker. It may participate in the targeting and clustering of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (AIS).