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Ankyrin G - 386 003

A membrane-cytoskeleton linker
Polyclonal rabbit purified antibody
Cat. No.: 386 003
Amount: 50 µg
Price: $370.00
Cat. No. 386 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 500      gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 1784 to 1961 from mouse AnkyrinG (UniProt Id: G5E8K5-1)
Reactivity Reacts with: rat (O70511-1), mouse (G5E8K5-1).
Other species not tested yet.
Specificity Specific for Ankyrin G, detects all described splice variants.
Data sheet 386_003.pdf

References for Ankyrin G - 386 003

Neuregulins 1, 2, and 3 Promote Early Neurite Outgrowth in ErbB4-Expressing Cortical GABAergic Interneurons.
Rahman-Enyart A, Lai C, Prieto AL
Molecular neurobiology (2020) : . 386 003 ICC; tested species: rat
Phosphorylation on Ser 359 of the α2 subunit in GABA type A receptors down-regulates their density at inhibitory synapses.
Nakamura Y, Morrow DH, Nathanson AJ, Henley JM, Wilkinson KA, Moss SJ
The Journal of biological chemistry (2020) : . 386 003 ICC; tested species: rat
Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment.
Alpizar SA, Baker AL, Gulledge AT, Hoppa MB
Frontiers in cellular neuroscience (2019) 13: 1. 386 003 ICC; tested species: rat
Deletion of class II ARFs in mice causes tremor by the Nav1.6 loss in cerebellar Purkinje cell axon initial segments.
Hosoi N, Shibasaki K, Hosono M, Konno A, Shinoda Y, Kiyonari H, Inoue K, Muramatsu SI, Ishizaki Y, Hirai H, Furuichi T, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 386 003 IHC; tested species: mouse
Cat. No.: 386 003
Quantity: 50 µg
Price: $370.00
Neuregulins 1, 2, and 3 Promote Early Neurite Outgrowth in ErbB4-Expressing Cortical GABAergic Interneurons.
Rahman-Enyart A, Lai C, Prieto AL
Molecular neurobiology (2020) : . 386 003 ICC; tested species: rat
Phosphorylation on Ser 359 of the α2 subunit in GABA type A receptors down-regulates their density at inhibitory synapses.
Nakamura Y, Morrow DH, Nathanson AJ, Henley JM, Wilkinson KA, Moss SJ
The Journal of biological chemistry (2020) : . 386 003 ICC; tested species: rat
Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment.
Alpizar SA, Baker AL, Gulledge AT, Hoppa MB
Frontiers in cellular neuroscience (2019) 13: 1. 386 003 ICC; tested species: rat
Deletion of class II ARFs in mice causes tremor by the Nav1.6 loss in cerebellar Purkinje cell axon initial segments.
Hosoi N, Shibasaki K, Hosono M, Konno A, Shinoda Y, Kiyonari H, Inoue K, Muramatsu SI, Ishizaki Y, Hirai H, Furuichi T, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2019) : . 386 003 IHC; tested species: mouse
Background
Ankyrin G is a membrane-cytoskeleton linker. It may participate in the targeting and clustering of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (AIS).