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Active Zone - 364 003

Site of synaptic vesicle release
Polyclonal rabbit purified antibody
Cat. No.: 364 003
Amount: 50 µg
Price: $370.00
Cat. No. 364 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: not recommended
IP: not recommended
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 466 from rat Rim2 (UniProt Id: Q9JIS1)
Reactivity Reacts with: rat (Q9JIS1), mouse.
Other species not tested yet.
Specificity Detects Rim 1, Rim 2 and Piccolo. Antiserum has been affinity purified with a synthetic peptide corresponding to aa 41-59 in mouse Piccolo. This epitope is conserved in Rim 1,
Data sheet 364_003.pdf

References for Active Zone - 364 003

Homozygous Expression of Mutant ELOVL4 Leads to Seizures and Death in a Novel Animal Model of Very Long-Chain Fatty Acid Deficiency.
Hopiavuori BR, Deák F, Wilkerson JL, Brush RS, Rocha-Hopiavuori NA, Hopiavuori AR, Ozan KG, Sullivan MT, Wren JD, Georgescu C, Szweda L, et al.
Molecular neurobiology (2018) 552: 1795-1813. 364 003 ICC; tested species: mouse
Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses.
Löhner M, Babai N, Müller T, Gierke K, Atorf J, Joachimsthaler A, Peukert A, Martens H, Feigenspan A, Kremers J, Schoch S, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3733: 7848-7863. 364 003 ICC, IHC; tested species: mouse
Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses.
Löhner M, Babai N, Müller T, Gierke K, Atorf J, Joachimsthaler A, Peukert A, Martens H, Feigenspan A, Kremers J, Schoch S, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3733: 7848-7863. 364 003 ICC, IHC; tested species: mouse
Cat. No.: 364 003
Quantity: 50 µg
Price: $370.00
Homozygous Expression of Mutant ELOVL4 Leads to Seizures and Death in a Novel Animal Model of Very Long-Chain Fatty Acid Deficiency.
Hopiavuori BR, Deák F, Wilkerson JL, Brush RS, Rocha-Hopiavuori NA, Hopiavuori AR, Ozan KG, Sullivan MT, Wren JD, Georgescu C, Szweda L, et al.
Molecular neurobiology (2018) 552: 1795-1813. 364 003 ICC; tested species: mouse
Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses.
Löhner M, Babai N, Müller T, Gierke K, Atorf J, Joachimsthaler A, Peukert A, Martens H, Feigenspan A, Kremers J, Schoch S, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3733: 7848-7863. 364 003 ICC, IHC; tested species: mouse
Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses.
Löhner M, Babai N, Müller T, Gierke K, Atorf J, Joachimsthaler A, Peukert A, Martens H, Feigenspan A, Kremers J, Schoch S, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3733: 7848-7863. 364 003 ICC, IHC; tested species: mouse
Background
The active zone is the region in the presynaptic nerve terminal that mediates neurotransmitter release. It consists of the presynaptic membrane and a dense protein structure called the cytomatrix at the active zone (CAZ).